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Multiple genes in a single GWAS risk locus synergistically mediate aberrant synaptic development and function in human neurons.
Zhang S, Zhang H, Forrest MP, Zhou Y, Sun X, Bagchi VA, Kozlova A, Santos MD, Piguel NH, Dionisio LE, Sanders AR, Pang ZP, He X, Penzes P, Duan J. Zhang S, et al. Among authors: penzes p. Cell Genom. 2023 Aug 28;3(9):100399. doi: 10.1016/j.xgen.2023.100399. eCollection 2023 Sep 13. Cell Genom. 2023. PMID: 37719141 Free PMC article.
Open Chromatin Profiling in hiPSC-Derived Neurons Prioritizes Functional Noncoding Psychiatric Risk Variants and Highlights Neurodevelopmental Loci.
Forrest MP, Zhang H, Moy W, McGowan H, Leites C, Dionisio LE, Xu Z, Shi J, Sanders AR, Greenleaf WJ, Cowan CA, Pang ZP, Gejman PV, Penzes P, Duan J. Forrest MP, et al. Among authors: penzes p. Cell Stem Cell. 2017 Sep 7;21(3):305-318.e8. doi: 10.1016/j.stem.2017.07.008. Epub 2017 Aug 10. Cell Stem Cell. 2017. PMID: 28803920 Free PMC article.
Autism Genetics: Over 100 Risk Genes and Counting.
Forrest MP, Penzes P. Forrest MP, et al. Among authors: penzes p. Pediatr Neurol Briefs. 2020 Dec 4;34:13. doi: 10.15844/pedneurbriefs-34-13. Pediatr Neurol Briefs. 2020. PMID: 33304087 Free PMC article.
Excitatory Dysfunction Drives Network and Calcium Handling Deficits in 16p11.2 Duplication Schizophrenia Induced Pluripotent Stem Cell-Derived Neurons.
Parnell E, Culotta L, Forrest MP, Jalloul HA, Eckman BL, Loizzo DD, Horan KKE, Dos Santos M, Piguel NH, Tai DJC, Zhang H, Gertler TS, Simkin D, Sanders AR, Talkowski ME, Gejman PV, Kiskinis E, Duan J, Penzes P. Parnell E, et al. Among authors: penzes p. Biol Psychiatry. 2023 Jul 15;94(2):153-163. doi: 10.1016/j.biopsych.2022.11.005. Epub 2022 Nov 9. Biol Psychiatry. 2023. PMID: 36581494 Free PMC article.
Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub.
Forrest MP, Dos Santos M, Piguel NH, Wang YZ, Hawkins NA, Bagchi VA, Dionisio LE, Yoon S, Simkin D, Martin-de-Saavedra MD, Gao R, Horan KE, George AL Jr, LeDoux MS, Kearney JA, Savas JN, Penzes P. Forrest MP, et al. Among authors: penzes p. Nat Commun. 2023 Feb 17;14(1):825. doi: 10.1038/s41467-023-36087-x. Nat Commun. 2023. PMID: 36808153 Free PMC article.
Dendritic structural plasticity and neuropsychiatric disease.
Forrest MP, Parnell E, Penzes P. Forrest MP, et al. Among authors: penzes p. Nat Rev Neurosci. 2018 Mar 16;19(4):215-234. doi: 10.1038/nrn.2018.16. Nat Rev Neurosci. 2018. PMID: 29545546 Free PMC article. Review.
118 results