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Pharmacological inhibition of TBK1/IKKε blunts immunopathology in a murine model of SARS-CoV-2 infection.
Ullah TR, Johansen MD, Balka KR, Ambrose RL, Gearing LJ, Roest J, Vivian JP, Sapkota S, Jayasekara WSN, Wenholz DS, Aldilla VR, Zeng J, Miemczyk S, Nguyen DH, Hansbro NG, Venkatraman R, Kang JH, Pang ES, Thomas BJ, Alharbi AS, Rezwan R, O'Keeffe M, Donald WA, Ellyard JI, Wong W, Kumar N, Kile BT, Vinuesa CG, Kelly GE, Laczka OF, Hansbro PM, De Nardo D, Gantier MP. Ullah TR, et al. Among authors: vivian jp. Nat Commun. 2023 Sep 18;14(1):5666. doi: 10.1038/s41467-023-41381-9. Nat Commun. 2023. PMID: 37723181 Free PMC article.
A pocket guide on how to structure SARS-CoV-2 drugs and therapies.
Littler DR, MacLachlan BJ, Watson GM, Vivian JP, Gully BS. Littler DR, et al. Among authors: vivian jp. Biochem Soc Trans. 2020 Dec 18;48(6):2625-2641. doi: 10.1042/BST20200396. Biochem Soc Trans. 2020. PMID: 33258925 Free PMC article. Review.
Structural and regulatory diversity shape HLA-C protein expression levels.
Kaur G, Gras S, Mobbs JI, Vivian JP, Cortes A, Barber T, Kuttikkatte SB, Jensen LT, Attfield KE, Dendrou CA, Carrington M, McVean G, Purcell AW, Rossjohn J, Fugger L. Kaur G, et al. Among authors: vivian jp. Nat Commun. 2017 Jun 26;8:15924. doi: 10.1038/ncomms15924. Nat Commun. 2017. PMID: 28649982 Free PMC article.
Structural plasticity of KIR2DL2 and KIR2DL3 enables altered docking geometries atop HLA-C.
Moradi S, Stankovic S, O'Connor GM, Pymm P, MacLachlan BJ, Faoro C, Retière C, Sullivan LC, Saunders PM, Widjaja J, Cox-Livingstone S, Rossjohn J, Brooks AG, Vivian JP. Moradi S, et al. Among authors: vivian jp. Nat Commun. 2021 Apr 12;12(1):2173. doi: 10.1038/s41467-021-22359-x. Nat Commun. 2021. PMID: 33846289 Free PMC article.
Polymorphic KIR3DL3 expression modulates tissue-resident and innate-like T cells.
Palmer WH, Leaton LA, Campos Codo A, Crute B, Roest J, Zhu S, Petersen J, Tobin RP, Hume PS, Stone M, van Bokhoven A, Gerich ME, McCarter MD, Zhu Y, Janssen WJ, Vivian JP, Trowsdale J, Getahun A, Rossjohn J, Cambier J, Loh L, Norman PJ. Palmer WH, et al. Among authors: vivian jp. Sci Immunol. 2023 Jun 30;8(84):eade5343. doi: 10.1126/sciimmunol.ade5343. Epub 2023 Jun 30. Sci Immunol. 2023. PMID: 37390222 Free PMC article.
63 results