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Galactose-modified iNKT cell agonists stabilized by an induced fit of CD1d prevent tumour metastasis.
Aspeslagh S, Li Y, Yu ED, Pauwels N, Trappeniers M, Girardi E, Decruy T, Van Beneden K, Venken K, Drennan M, Leybaert L, Wang J, Franck RW, Van Calenbergh S, Zajonc DM, Elewaut D. Aspeslagh S, et al. Among authors: trappeniers m. EMBO J. 2011 Jun 1;30(11):2294-305. doi: 10.1038/emboj.2011.145. Epub 2011 May 6. EMBO J. 2011. PMID: 21552205 Free PMC article.
The synthesis and in vivo evaluation of 2',2'-difluoro KRN7000.
Leung L, Tomassi C, Van Beneden K, Decruy T, Trappeniers M, Elewaut D, Gao Y, Elliott T, Al-Shamkhani A, Ottensmeier C, Werner JM, Williams A, Van Calenbergh S, Linclau B. Leung L, et al. Among authors: trappeniers m. ChemMedChem. 2009 Mar;4(3):329-34. doi: 10.1002/cmdc.200800348. ChemMedChem. 2009. PMID: 19137519
Synthesis and in vitro evaluation of alpha-GalCer epimers.
Trappeniers M, Goormans S, Van Beneden K, Decruy T, Linclau B, Al-Shamkhani A, Elliott T, Ottensmeier C, Werner JM, Elewaut D, Van Calenbergh S. Trappeniers M, et al. ChemMedChem. 2008 Jul;3(7):1061-70. doi: 10.1002/cmdc.200800021. ChemMedChem. 2008. PMID: 18418814