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A promoterless AAV6.2FF-based lung gene editing platform for the correction of surfactant protein B deficiency.
Thomas SP, Domm JM, van Vloten JP, Xu L, Vadivel A, Yates JGE, Pei Y, Ingrao J, van Lieshout LP, Jackson SR, Minott JA, Achuthan A, Mehrani Y, McAusland TM, Zhang W, Karimi K, Vaughan AE, de Jong J, Kang MH, Thebaud B, Wootton SK. Thomas SP, et al. Among authors: xu l. Mol Ther. 2023 Dec 6;31(12):3457-3477. doi: 10.1016/j.ymthe.2023.10.002. Epub 2023 Oct 7. Mol Ther. 2023. PMID: 37805711 Free article.
A lung tropic AAV vector improves survival in a mouse model of surfactant B deficiency.
Kang MH, van Lieshout LP, Xu L, Domm JM, Vadivel A, Renesme L, Mühlfeld C, Hurskainen M, Mižíková I, Pei Y, van Vloten JP, Thomas SP, Milazzo C, Cyr-Depauw C, Whitsett JA, Nogee LM, Wootton SK, Thébaud B. Kang MH, et al. Among authors: xu l. Nat Commun. 2020 Aug 6;11(1):3929. doi: 10.1038/s41467-020-17577-8. Nat Commun. 2020. PMID: 32764559 Free PMC article.
Pulmonary and Neurologic Effects of Mesenchymal Stromal Cell Extracellular Vesicles in a Multifactorial Lung Injury Model.
Lithopoulos MA, Strueby L, O'Reilly M, Zhong S, Möbius MA, Eaton F, Fung M, Hurskainen M, Cyr-Depauw C, Suen C, Xu L, Collins JJP, Vadivel A, Stewart DJ, Burger D, Thébaud B. Lithopoulos MA, et al. Among authors: xu l. Am J Respir Crit Care Med. 2022 May 15;205(10):1186-1201. doi: 10.1164/rccm.202012-4520OC. Am J Respir Crit Care Med. 2022. PMID: 35286238
Neonatal hyperoxia in mice triggers long-term cognitive deficits via impairments in cerebrovascular function and neurogenesis.
Lithopoulos MA, Toussay X, Zhong S, Xu L, Mustafa SB, Ouellette J, Freitas-Andrade M, Comin CH, Bassam HA, Baker AN, Sun Y, Wakem M, Moreira AG, Blanco CL, Vadivel A, Tsilfidis C, Seidner SR, Slack RS, Lagace DC, Wang J, Lacoste B, Thébaud B. Lithopoulos MA, et al. Among authors: xu l. J Clin Invest. 2022 Nov 15;132(22):e146095. doi: 10.1172/JCI146095. J Clin Invest. 2022. PMID: 36136598 Free PMC article.
Single-Cell RNA Sequencing Reveals Repair Features of Human Umbilical Cord Mesenchymal Stromal Cells.
Cyr-Depauw C, Cook DP, Mižik I, Lesage F, Vadivel A, Renesme L, Deng Y, Zhong S, Bardin P, Xu L, Möbius MA, Marzahn J, Freund D, Stewart DJ, Vanderhyden BC, Rüdiger M, Thébaud B. Cyr-Depauw C, et al. Among authors: xu l. Am J Respir Crit Care Med. 2024 Apr 2. doi: 10.1164/rccm.202310-1975OC. Online ahead of print. Am J Respir Crit Care Med. 2024. PMID: 38564376
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