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FTLD targets brain regions expressing recently evolved genes.
Pasquini L, Pereira FL, Seddighi S, Zeng Y, Wei Y, Illán-Gala I, Vatsavayai SC, Friedberg A, Lee AJ, Brown JA, Spina S, Grinberg LT, Sirkis DW, Bonham LW, Yokoyama JS, Boxer AL, Kramer JH, Rosen HJ, Humphrey J, Gitler AD, Miller BL, Pollard KS, Ward ME, Seeley WW. Pasquini L, et al. Among authors: bonham lw. medRxiv [Preprint]. 2023 Oct 28:2023.10.27.23297687. doi: 10.1101/2023.10.27.23297687. medRxiv. 2023. PMID: 37961381 Free PMC article. Preprint.
Toll-Like Receptor 4 Agonist Injection With Concurrent Radiotherapy in Patients With Metastatic Soft Tissue Sarcoma: A Phase 1 Nonrandomized Controlled Trial.
Seo YD, Lu H, Black G, Smythe K, Yu Y, Hsu C, Ng J, Hermida de Viveiros P, Warren EH, Schroeder BA, O'Malley RB, Cranmer LD, Loggers ET, Wagner MJ, Bonham L, Pillarisetty VG, Kane G, Berglund P, Hsu FJ, Mi X, Alexiev BA, Pierce RH, Riddell SR, Jones RL, Ter Meulen J, Kim EY, Pollack SM. Seo YD, et al. Among authors: bonham l. JAMA Oncol. 2023 Dec 1;9(12):1660-1668. doi: 10.1001/jamaoncol.2023.4015. JAMA Oncol. 2023. PMID: 37824131 Free PMC article. Clinical Trial.
Early-onset Alzheimer's disease explained by polygenic risk of late-onset disease?
Mantyh WG, Cochran JN, Taylor JW, Broce IJ, Geier EG, Bonham LW, Anderson AG, Sirkis DW, Joie R, Iaccarino L, Chaudhary K, Edwards L, Strom A, Grant H, Allen IE, Miller ZA, Gorno-Tempini ML, Kramer JH, Miller BL, Desikan RS, Rabinovici GD, Yokoyama JS. Mantyh WG, et al. Among authors: bonham lw. Alzheimers Dement (Amst). 2023 Sep 28;15(4):e12482. doi: 10.1002/dad2.12482. eCollection 2023 Oct-Dec. Alzheimers Dement (Amst). 2023. PMID: 37780862 Free PMC article.
C9orf72 gene networks in the human brain correlate with cortical thickness in C9-FTD and implicate vulnerable cell types.
Broce IJ, Sirkis DW, Nillo RM, Bonham LW, Lee SE, Miller B, Castruita P, Sturm VE, Sugrue LS, Desikan RS, Yokoyama JS. Broce IJ, et al. Among authors: bonham lw. bioRxiv [Preprint]. 2023 Aug 3:2023.07.17.549377. doi: 10.1101/2023.07.17.549377. bioRxiv. 2023. Update in: Front Neurosci. 2024 Feb 26;18:1258996. doi: 10.3389/fnins.2024.1258996. PMID: 37503230 Free PMC article. Updated. Preprint.
Prevalence, Timing, and Network Localization of Emergent Visual Creativity in Frontotemporal Dementia.
Friedberg A, Pasquini L, Diggs R, Glaubitz EA, Lopez L, Illán-Gala I, Iaccarino L, La Joie R, Mundada N, Knudtson M, Neylan K, Brown J, Allen IE, Rankin KP, Bonham LW, Yokoyama JS, Ramos EM, Geschwind DH, Spina S, Grinberg LT, Miller ZA, Kramer JH, Rosen H, Gorno-Tempini ML, Rabinovici G, Seeley WW, Miller BL. Friedberg A, et al. Among authors: bonham lw. JAMA Neurol. 2023 Apr 1;80(4):377-387. doi: 10.1001/jamaneurol.2023.0001. JAMA Neurol. 2023. PMID: 36848111 Free PMC article.
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