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Structure-based lead optimization to improve potency and selectivity of a novel tetrahydroimidazo[1,2-a]pyridine-5-carboxylic acid series of heparanase-1 inhibitor.
Imai Y, Suzuki R, Wakasugi D, Matsuda D, Tanaka-Yamamoto N, Ohki Y, Mima M, Endo M, Tabata R, Matsuzawa H, Hasegawa Y, Kato S, Sugisaki M, Miyagawa H, Fujimoto N, Fukunaga T, Kato S, Takahashi T, Kakinuma H. Imai Y, et al. Among authors: wakasugi d. Bioorg Med Chem. 2023 Oct 1;93:117460. doi: 10.1016/j.bmc.2023.117460. Epub 2023 Aug 26. Bioorg Med Chem. 2023. PMID: 37660465
A case of acute diffuse large B cell lymphoma in an anti-human T-cell leukaemia virus type 1-positive rheumatoid arthritis patient treated with methotrexate, who died.
Yoshida N, Sugiyama G, Sugi S, Satake K, Wakasugi D, Yamasaki S, Mihara Y, Matsuda K, Ida H, Ohshima K, Yamaguchi R, Nakashima M. Yoshida N, et al. Among authors: wakasugi d. Mod Rheumatol Case Rep. 2020 Jul;4(2):161-167. doi: 10.1080/24725625.2019.1702493. Epub 2019 Dec 31. Mod Rheumatol Case Rep. 2020. PMID: 33087004
Effectiveness of cryofiltration and mizoribine combination with oral steroid therapy in a patient with membranoproliferative glomerulonephritis due to essential cryoglobulinemia.
Kurokawa Y, Koike K, Kaida Y, Ito S, Chiba H, Urae K, Moriyama T, Nakamura N, Imai T, Shibata R, Hazama T, Wakasugi D, Okuda S, Fukami K. Kurokawa Y, et al. Among authors: wakasugi d. CEN Case Rep. 2019 Aug;8(3):205-211. doi: 10.1007/s13730-019-00394-4. Epub 2019 Mar 29. CEN Case Rep. 2019. PMID: 30927247 Free PMC article.
The Successful Treatment of Myeloperoxidase Antineutrophil Cytoplasmic Antibody-positive Hypertrophic Pachymeningitis in Patients with the Limited Form of Granulomatosis with Polyangiitis Using Methotrexate: Two Case Reports.
Kaieda S, Yoshida N, Minezaki M, Ushijima S, Wakasugi D, Miura S, Uchiyama Y, Ida H, Hoshino T. Kaieda S, et al. Among authors: wakasugi d. Intern Med. 2017;56(8):959-965. doi: 10.2169/internalmedicine.56.7742. Epub 2017 Apr 15. Intern Med. 2017. PMID: 28420847 Free PMC article.
Association of anti-aminoacyl-transfer RNA synthetase antibody and anti-melanoma differentiation-associated gene 5 antibody with the therapeutic response of polymyositis/dermatomyositis-associated interstitial lung disease.
Yoshida N, Okamoto M, Kaieda S, Fujimoto K, Ebata T, Tajiri M, Nakamura M, Tominaga M, Wakasugi D, Kawayama T, Kuwana M, Mimori T, Ida H, Hoshino T. Yoshida N, et al. Among authors: wakasugi d. Respir Investig. 2017 Jan;55(1):24-32. doi: 10.1016/j.resinv.2016.08.007. Epub 2016 Sep 30. Respir Investig. 2017. PMID: 28012490
An Autopsy Case of Anti-melanoma Differentiation-associated Gene-5 Antibody-positive Clinical Amyopathic Dermatomyositis Complicated by Rapidly Progressive Interstitial Lung Disease.
Yoshida N, Kaieda S, Tomozoe K, Tajiri M, Wakasugi D, Okamoto M, Tominaga M, Ida H, Hoshino T. Yoshida N, et al. Among authors: wakasugi d. Intern Med. 2016;55(12):1653-9. doi: 10.2169/internalmedicine.55.6055. Epub 2016 Jun 15. Intern Med. 2016. PMID: 27301523 Free article.
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