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Monomeric α-synuclein activates the plasma membrane calcium pump.
Kowalski A, Betzer C, Larsen ST, Gregersen E, Newcombe EA, Bermejo MC, Bendtsen VW, Diemer J, Ernstsen CV, Jain S, Bou AE, Langkilde AE, Nejsum LN, Klipp E, Edwards R, Kragelund BB, Jensen PH, Nissen P. Kowalski A, et al. Among authors: edwards r. EMBO J. 2023 Dec 1;42(23):e111122. doi: 10.15252/embj.2022111122. Epub 2023 Nov 2. EMBO J. 2023. PMID: 37916890 Free PMC article.
Alpha-synuclein research: defining strategic moves in the battle against Parkinson's disease.
Oliveira LMA, Gasser T, Edwards R, Zweckstetter M, Melki R, Stefanis L, Lashuel HA, Sulzer D, Vekrellis K, Halliday GM, Tomlinson JJ, Schlossmacher M, Jensen PH, Schulze-Hentrich J, Riess O, Hirst WD, El-Agnaf O, Mollenhauer B, Lansbury P, Outeiro TF. Oliveira LMA, et al. Among authors: edwards r. NPJ Parkinsons Dis. 2021 Jul 26;7(1):65. doi: 10.1038/s41531-021-00203-9. NPJ Parkinsons Dis. 2021. PMID: 34312398 Free PMC article. Review.
Direct membrane association drives mitochondrial fission by the Parkinson disease-associated protein alpha-synuclein.
Nakamura K, Nemani VM, Azarbal F, Skibinski G, Levy JM, Egami K, Munishkina L, Zhang J, Gardner B, Wakabayashi J, Sesaki H, Cheng Y, Finkbeiner S, Nussbaum RL, Masliah E, Edwards RH. Nakamura K, et al. J Biol Chem. 2011 Jun 10;286(23):20710-26. doi: 10.1074/jbc.M110.213538. Epub 2011 Apr 13. J Biol Chem. 2011. PMID: 21489994 Free PMC article.
The function of α-synuclein.
Bendor JT, Logan TP, Edwards RH. Bendor JT, et al. Neuron. 2013 Sep 18;79(6):1044-66. doi: 10.1016/j.neuron.2013.09.004. Neuron. 2013. PMID: 24050397 Free PMC article.
The behavior of alpha-synuclein in neurons.
Fortin DL, Nemani VM, Nakamura K, Edwards RH. Fortin DL, et al. Mov Disord. 2010;25 Suppl 1:S21-6. doi: 10.1002/mds.22722. Mov Disord. 2010. PMID: 20187244
5,261 results