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TDP2 protects transcription from abortive topoisomerase activity and is required for normal neural function.
Gómez-Herreros F, Schuurs-Hoeijmakers JH, McCormack M, Greally MT, Rulten S, Romero-Granados R, Counihan TJ, Chaila E, Conroy J, Ennis S, Delanty N, Cortés-Ledesma F, de Brouwer AP, Cavalleri GL, El-Khamisy SF, de Vries BB, Caldecott KW. Gómez-Herreros F, et al. Nat Genet. 2014 May;46(5):516-21. doi: 10.1038/ng.2929. Epub 2014 Mar 23. Nat Genet. 2014. PMID: 24658003
FUS (fused in sarcoma) is a component of the cellular response to topoisomerase I-induced DNA breakage and transcriptional stress.
Martinez-Macias MI, Moore DA, Green RL, Gomez-Herreros F, Naumann M, Hermann A, Van Damme P, Hafezparast M, Caldecott KW. Martinez-Macias MI, et al. Among authors: gomez herreros f. Life Sci Alliance. 2019 Feb 26;2(2):e201800222. doi: 10.26508/lsa.201800222. Print 2019 Apr. Life Sci Alliance. 2019. PMID: 30808650 Free PMC article.
Feedback regulation of ribosome assembly.
de la Cruz J, Gómez-Herreros F, Rodríguez-Galán O, Begley V, de la Cruz Muñoz-Centeno M, Chávez S. de la Cruz J, et al. Among authors: gomez herreros f. Curr Genet. 2018 Apr;64(2):393-404. doi: 10.1007/s00294-017-0764-x. Epub 2017 Oct 11. Curr Genet. 2018. PMID: 29022131 Review.
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