Kowol CR - Search Results

1

In vitro biodistribution studies on clinically approved FGFR inhibitors ponatinib, nintedanib, erlotinib and the investigational inhibitor KP2692.

Dömötör O, Mathuber M, Kowol CR. Dömötör O, et al. Among authors: kowol cr. Eur J Pharm Sci. 2024 Jan 1;192:106651. doi: 10.1016/j.ejps.2023.106651. Epub 2023 Nov 25. Eur J Pharm Sci. 2024. PMID: 38013124 Free article.

2

Ribonucleotide reductase inhibition by metal complexes of Triapine (3-aminopyridine-2-carboxaldehyde thiosemicarbazone): a combined experimental and theoretical study.

Popović-Bijelić A, Kowol CR, Lind ME, Luo J, Himo F, Enyedy EA, Arion VB, Gräslund A. Popović-Bijelić A, et al. Among authors: kowol cr. J Inorg Biochem. 2011 Nov;105(11):1422-31. doi: 10.1016/j.jinorgbio.2011.07.003. Epub 2011 Jul 31. J Inorg Biochem. 2011. PMID: 21955844 Free PMC article.

3

Enhanced anticancer activity and circumvention of resistance mechanisms by novel polymeric/ phospholipidic nanocarriers of doxorubicin.

Senkiv Y, Riabtseva A, Heffeter P, Boiko N, Kowol CR, Jungwith U, Shlyakhtina Y, Garasevych SG, Mitina N, Berger W, Zaichenko A, Stoika R. Senkiv Y, et al. Among authors: kowol cr. J Biomed Nanotechnol. 2014 Jul;10(7):1369-81. doi: 10.1166/jbn.2014.1864. J Biomed Nanotechnol. 2014. PMID: 24804557

4

Nanoformulation improves activity of the (pre)clinical anticancer ruthenium complex KP1019.

Heffeter P, Riabtseva A, Senkiv Y, Kowol CR, Körner W, Jungwith U, Mitina N, Keppler BK, Konstantinova T, Yanchuk I, Stoika R, Zaichenko A, Berger W. Heffeter P, et al. Among authors: kowol cr. J Biomed Nanotechnol. 2014 May;10(5):877-84. doi: 10.1166/jbn.2014.1763. J Biomed Nanotechnol. 2014. PMID: 24734541

5

Structure elucidation and quantification of the reduction products of anticancer Pt(iv) prodrugs by electrochemistry/mass spectrometry (EC-MS).

Frensemeier LM , Mayr J , Koellensperger G , Keppler BK , Kowol CR , Karst U . Frensemeier LM , et al. Among authors: kowol cr. Analyst. 2018 Apr 30;143(9):1997-2001. doi: 10.1039/c8an00258d. Analyst. 2018. PMID: 29629473 Free PMC article.

6

Maleimide-functionalised platinum(IV) complexes as a synthetic platform for targeted drug delivery.

Pichler V, Mayr J, Heffeter P, Dömötör O, Enyedy ÉA, Hermann G, Groza D, Köllensperger G, Galanksi M, Berger W, Keppler BK, Kowol CR. Pichler V, et al. Among authors: kowol cr. Chem Commun (Camb). 2013 Mar 18;49(22):2249-2251. doi: 10.1039/c3cc39258a. Chem Commun (Camb). 2013. PMID: 23396381 Free PMC article.

7

Comparative studies on the human serum albumin binding of the clinically approved EGFR inhibitors gefitinib, erlotinib, afatinib, osimertinib and the investigational inhibitor KP2187.

Dömötör O, Pelivan K, Borics A, Keppler BK, Kowol CR, Enyedy ÉA. Dömötör O, et al. Among authors: kowol cr. J Pharm Biomed Anal. 2018 May 30;154:321-331. doi: 10.1016/j.jpba.2018.03.011. Epub 2018 Mar 11. J Pharm Biomed Anal. 2018. PMID: 29567575 Free article.

8

Synthesis, Characterization and in vitro Studies of a Cathepsin B-Cleavable Prodrug of the VEGFR Inhibitor Sunitinib.

Karnthaler-Benbakka C, Koblmüller B, Mathuber M, Holste K, Berger W, Heffeter P, Kowol CR, Keppler BK. Karnthaler-Benbakka C, et al. Among authors: kowol cr. Chem Biodivers. 2019 Jan;16(1):e1800520. doi: 10.1002/cbdv.201800520. Epub 2018 Dec 19. Chem Biodivers. 2019. PMID: 30566287 Free PMC article.

9

Cancer Cell Resistance Against the Clinically Investigated Thiosemicarbazone COTI-2 Is Based on Formation of Intracellular Copper Complex Glutathione Adducts and ABCC1-Mediated Efflux.

Bormio Nunes JH, Hager S, Mathuber M, Pósa V, Roller A, Enyedy ÉA, Stefanelli A, Berger W, Keppler BK, Heffeter P, Kowol CR. Bormio Nunes JH, et al. Among authors: kowol cr. J Med Chem. 2020 Nov 25;63(22):13719-13732. doi: 10.1021/acs.jmedchem.0c01277. Epub 2020 Nov 15. J Med Chem. 2020. PMID: 33190481 Free PMC article.

10

Improving the Stability of EGFR Inhibitor Cobalt(III) Prodrugs.

Mathuber M, Schueffl H, Dömötör O, Karnthaler C, Enyedy ÉA, Heffeter P, Keppler BK, Kowol CR. Mathuber M, et al. Among authors: kowol cr. Inorg Chem. 2020 Dec 7;59(23):17794-17810. doi: 10.1021/acs.inorgchem.0c03083. Epub 2020 Nov 21. Inorg Chem. 2020. PMID: 33222438 Free PMC article.

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