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Single-cell sequencing reveals the origin and the order of mutation acquisition in T-cell acute lymphoblastic leukemia.
De Bie J, Demeyer S, Alberti-Servera L, Geerdens E, Segers H, Broux M, De Keersmaecker K, Michaux L, Vandenberghe P, Voet T, Boeckx N, Uyttebroeck A, Cools J. De Bie J, et al. Among authors: de keersmaecker k. Leukemia. 2018 Jun;32(6):1358-1369. doi: 10.1038/s41375-018-0127-8. Epub 2018 Apr 18. Leukemia. 2018. PMID: 29740158 Free PMC article.
Single-cell DNA amplicon sequencing reveals clonal heterogeneity and evolution in T-cell acute lymphoblastic leukemia.
Albertí-Servera L, Demeyer S, Govaerts I, Swings T, De Bie J, Gielen O, Brociner M, Michaux L, Maertens J, Uyttebroeck A, De Keersmaecker K, Boeckx N, Segers H, Cools J. Albertí-Servera L, et al. Among authors: de bie j, de keersmaecker k. Blood. 2021 Feb 11;137(6):801-811. doi: 10.1182/blood.2020006996. Blood. 2021. PMID: 32812017 Free PMC article.
Monitoring of Leukemia Clones in B-cell Acute Lymphoblastic Leukemia at Diagnosis and During Treatment by Single-cell DNA Amplicon Sequencing.
Meyers S, Alberti-Servera L, Gielen O, Erard M, Swings T, De Bie J, Michaux L, Dewaele B, Boeckx N, Uyttebroeck A, De Keersmaecker K, Maertens J, Segers H, Cools J, Demeyer S. Meyers S, et al. Among authors: de bie j. Hemasphere. 2022 Mar 10;6(4):e700. doi: 10.1097/HS9.0000000000000700. eCollection 2022 Apr. Hemasphere. 2022. PMID: 35291210 Free PMC article.
Hedgehog pathway activation in T-cell acute lymphoblastic leukemia predicts response to SMO and GLI1 inhibitors.
Dagklis A, Demeyer S, De Bie J, Radaelli E, Pauwels D, Degryse S, Gielen O, Vicente C, Vandepoel R, Geerdens E, Uyttebroeck A, Boeckx N, de Bock CE, Cools J. Dagklis A, et al. Among authors: de bie j, de bock ce. Blood. 2016 Dec 8;128(23):2642-2654. doi: 10.1182/blood-2016-03-703454. Epub 2016 Sep 30. Blood. 2016. PMID: 27694322 Free article.
The XPO1 Inhibitor KPT-8602 Synergizes with Dexamethasone in Acute Lymphoblastic Leukemia.
Verbeke D, Demeyer S, Prieto C, de Bock CE, De Bie J, Gielen O, Jacobs K, Mentens N, Verhoeven BM, Uyttebroeck A, Boeckx N, De Keersmaecker K, Maertens J, Segers H, Cools J. Verbeke D, et al. Among authors: de bie j, de keersmaecker k, de bock ce. Clin Cancer Res. 2020 Nov 1;26(21):5747-5758. doi: 10.1158/1078-0432.CCR-20-1315. Epub 2020 Aug 21. Clin Cancer Res. 2020. PMID: 32826328
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