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Targeting amyotrophic lateral sclerosis by neutralizing seeding-competent TDP-43 in CSF.
Audrain M, Egesipe AL, Tentillier N, Font L, Ratnam M, Mottier L, Clavel M, Le Roux-Bourdieu M, Fenyi A, Ollier R, Chevalier E, Guilhot F, Fuchs A, Piorkowska K, Carlyle B, Arnold SE, Berry JD, Luthi-Carter R, Adolfsson O, Pfeifer A, Kosco-Vilbois M, Seredenina T, Afroz T. Audrain M, et al. Among authors: fuchs a. Brain Commun. 2023 Nov 3;5(6):fcad306. doi: 10.1093/braincomms/fcad306. eCollection 2023. Brain Commun. 2023. PMID: 38025276 Free PMC article.
Improved antibody pharmacokinetics by disruption of contiguous positive surface potential and charge reduction using alternate human framework.
Ollier R, Fuchs A, Gauye F, Piorkowska K, Menant S, Ratnam M, Montanari P, Guilhot F, Phillipe D, Audrain M, Egesipe AL, Névoltris D, Seredenina T, Pfeifer A, Kosco-Vilbois M, Afroz T. Ollier R, et al. Among authors: fuchs a. MAbs. 2023 Jan-Dec;15(1):2232087. doi: 10.1080/19420862.2023.2232087. MAbs. 2023. PMID: 37408314 Free PMC article.
Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183.
de Vries LE, Jansen PAM, Barcelo C, Munro J, Verhoef JMJ, Pasaje CFA, Rubiano K, Striepen J, Abla N, Berning L, Bolscher JM, Demarta-Gatsi C, Henderson RWM, Huijs T, Koolen KMJ, Tumwebaze PK, Yeo T, Aguiar ACC, Angulo-Barturen I, Churchyard A, Baum J, Fernández BC, Fuchs A, Gamo FJ, Guido RVC, Jiménez-Diaz MB, Pereira DB, Rochford R, Roesch C, Sanz LM, Trevitt G, Witkowski B, Wittlin S, Cooper RA, Rosenthal PJ, Sauerwein RW, Schalkwijk J, Hermkens PHH, Bonnert RV, Campo B, Fidock DA, Llinás M, Niles JC, Kooij TWA, Dechering KJ. de Vries LE, et al. Among authors: fuchs a. Nat Commun. 2022 Apr 20;13(1):2158. doi: 10.1038/s41467-022-29688-5. Nat Commun. 2022. PMID: 35444200 Free PMC article.
Safety, pharmacokinetics, and antimalarial activity of the novel triaminopyrimidine ZY-19489: a first-in-human, randomised, placebo-controlled, double-blind, single ascending dose study, pilot food-effect study, and volunteer infection study.
Barber BE, Fernandez M, Patel HB, Barcelo C, Woolley SD, Patel H, Llewellyn S, Abd-Rahman AN, Sharma S, Jain M, Ghoghari A, Di Resta I, Fuchs A, Deni I, Yeo T, Mok S, Fidock DA, Chalon S, Möhrle JJ, Parmar D, McCarthy JS, Kansagra K. Barber BE, et al. Among authors: fuchs a. Lancet Infect Dis. 2022 Jun;22(6):879-890. doi: 10.1016/S1473-3099(21)00679-4. Epub 2022 Mar 2. Lancet Infect Dis. 2022. PMID: 35247321 Clinical Trial.
Aortic dimensions in women with previous pre-eclampsia.
Møller ELR, Hauge MG, Pham MHC, Damm P, Kofoed KF, Fuchs A, Kühl JT, Sigvardsen PE, Ersbøll AS, Johansen M, Nordestgaard BG, Køber LV, Gustafsson F, Linde JJ. Møller ELR, et al. Among authors: fuchs a. J Cardiovasc Comput Tomogr. 2024 Jun 11:S1934-5925(24)00343-5. doi: 10.1016/j.jcct.2024.06.001. Online ahead of print. J Cardiovasc Comput Tomogr. 2024. PMID: 38866633
Functional outcomes of diets in multiple sclerosis (FOOD for MS): Protocol for a parallel arm randomized feeding trial for low glycemic load and calorie restriction.
Martin K, Cofield SS, Cross AH, Goss AM, Raji CA, Rinker JR, Wu GF, Blair J, Fuchs A, Ghezzi L, Green K, Pace F, Pastori G, Taylor MG, Piccio L, Wingo BC. Martin K, et al. Among authors: fuchs a. Contemp Clin Trials. 2024 May 29;143:107584. doi: 10.1016/j.cct.2024.107584. Online ahead of print. Contemp Clin Trials. 2024. PMID: 38821260
Comparison of clinical outcomes in hospitalized patients with COVID-19 or non-COVID-19 community-acquired pneumonia in a prospective observational cohort study.
Meyer HJ, Mödl L, Unruh O, Xiang W, Berger S, Müller-Plathe M, Rohde G, Pletz MW, Rupp J, Suttorp N, Witzenrath M, Zoller T, Mittermaier M, Steinbeis F; CAPNETZ study group. Meyer HJ, et al. Infection. 2024 May 18. doi: 10.1007/s15010-024-02292-z. Online ahead of print. Infection. 2024. PMID: 38761325
1,484 results