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ROS-induced ribosome impairment underlies ZAKα-mediated metabolic decline in obesity and aging.
Snieckute G, Ryder L, Vind AC, Wu Z, Arendrup FS, Stoneley M, Chamois S, Martinez-Val A, Leleu M, Dreos R, Russell A, Gay DM, Genzor AV, Choi BS, Basse AL, Sass F, Dall M, Dollet LCM, Blasius M, Willis AE, Lund AH, Treebak JT, Olsen JV, Poulsen SS, Pownall ME, Jensen BAH, Clemmensen C, Gerhart-Hines Z, Gatfield D, Bekker-Jensen S. Snieckute G, et al. Among authors: poulsen ss. Science. 2023 Dec 8;382(6675):eadf3208. doi: 10.1126/science.adf3208. Epub 2023 Dec 8. Science. 2023. PMID: 38060659
Ribosome stalling is a signal for metabolic regulation by the ribotoxic stress response.
Snieckute G, Genzor AV, Vind AC, Ryder L, Stoneley M, Chamois S, Dreos R, Nordgaard C, Sass F, Blasius M, López AR, Brynjólfsdóttir SH, Andersen KL, Willis AE, Frankel LB, Poulsen SS, Gatfield D, Gerhart-Hines Z, Clemmensen C, Bekker-Jensen S. Snieckute G, et al. Among authors: poulsen ss. Cell Metab. 2022 Dec 6;34(12):2036-2046.e8. doi: 10.1016/j.cmet.2022.10.011. Epub 2022 Nov 15. Cell Metab. 2022. PMID: 36384144 Free PMC article.
High incidence of imperforate vagina in ADGRA3-deficient mice.
Kvam JM, Nybo ML, Torz L, Sustarsic RK, Jensen KHR, Nielsen JE, Frederiksen H, Gadgaard S, Spiess K, Poulsen SS, Thomsen JS, Cowin P, Blomberg Jensen M, Kurita T, Rosenkilde MM. Kvam JM, et al. Among authors: poulsen ss. BMC Biol. 2024 Apr 8;22(1):77. doi: 10.1186/s12915-024-01873-6. BMC Biol. 2024. PMID: 38589878 Free PMC article.
Genotoxicity in the absence of inflammation after tungsten inhalation in mice.
Sørli JB, Jensen ACØ, Mortensen A, Szarek J, Chatzigianelli E, Gutierrez CAT, Jacobsen NR, Poulsen SS, Hafez I, Loizides C, Biskos G, Hougaard KS, Vogel U, Hadrup N. Sørli JB, et al. Among authors: poulsen ss. Environ Toxicol Pharmacol. 2023 Mar;98:104074. doi: 10.1016/j.etap.2023.104074. Epub 2023 Jan 29. Environ Toxicol Pharmacol. 2023. PMID: 36724834 Free article.
302 results