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Matrix Metalloproteinase-7 in Urinary Extracellular Vesicles Identifies Rapid Disease Progression in Autosomal Dominant Polycystic Kidney Disease.
van Heugten MH, Blijdorp CJ, Arjune S, van Willigenburg H, Bezstarosti K, Demmers JAA, Musterd-Bhaggoe U, Meijer E, Gansevoort RT, Zietse R, Hayat S, Kramann R, Müller RU, Salih M, Hoorn EJ; DIPAK Consortium. van Heugten MH, et al. Among authors: kramann r. J Am Soc Nephrol. 2024 Mar 1;35(3):321-334. doi: 10.1681/ASN.0000000000000277. Epub 2023 Dec 11. J Am Soc Nephrol. 2024. PMID: 38073039
Fibrosis and Immune Cell Infiltration Are Separate Events Regulated by Cell-Specific Receptor Notch3 Expression.
Brandt S, Ballhause TM, Bernhardt A, Becker A, Salaru D, Le-Deffge HM, Fehr A, Fu Y, Philipsen L, Djudjaj S, Müller AJ, Kramann R, Ibrahim M, Geffers R, Siebel C, Isermann B, Heidel FH, Lindquist JA, Mertens PR. Brandt S, et al. Among authors: kramann r. J Am Soc Nephrol. 2020 Nov;31(11):2589-2608. doi: 10.1681/ASN.2019121289. Epub 2020 Aug 28. J Am Soc Nephrol. 2020. PMID: 32859670 Free PMC article.
Only Hyperuricemia with Crystalluria, but not Asymptomatic Hyperuricemia, Drives Progression of Chronic Kidney Disease.
Sellmayr M, Hernandez Petzsche MR, Ma Q, Krüger N, Liapis H, Brink A, Lenz B, Angelotti ML, Gnemmi V, Kuppe C, Kim H, Bindels EMJ, Tajti F, Saez-Rodriguez J, Lech M, Kramann R, Romagnani P, Anders HJ, Steiger S. Sellmayr M, et al. Among authors: kramann r. J Am Soc Nephrol. 2020 Dec;31(12):2773-2792. doi: 10.1681/ASN.2020040523. Epub 2020 Sep 16. J Am Soc Nephrol. 2020. PMID: 32938648 Free PMC article.
Deep Learning-Based Segmentation and Quantification in Experimental Kidney Histopathology.
Bouteldja N, Klinkhammer BM, Bülow RD, Droste P, Otten SW, Freifrau von Stillfried S, Moellmann J, Sheehan SM, Korstanje R, Menzel S, Bankhead P, Mietsch M, Drummer C, Lehrke M, Kramann R, Floege J, Boor P, Merhof D. Bouteldja N, et al. Among authors: kramann r. J Am Soc Nephrol. 2021 Jan;32(1):52-68. doi: 10.1681/ASN.2020050597. Epub 2020 Nov 5. J Am Soc Nephrol. 2021. PMID: 33154175 Free PMC article.
Guanidinylated Apolipoprotein C3 (ApoC3) Associates with Kidney and Vascular Injury.
Schunk SJ, Hermann J, Sarakpi T, Triem S, Lellig M, Hahm E, Zewinger S, Schmit D, Becker E, Möllmann J, Lehrke M, Kramann R, Boor P, Lipp P, Laufs U, März W, Reiser J, Jankowski J, Fliser D, Speer T, Jankowski V. Schunk SJ, et al. Among authors: kramann r. J Am Soc Nephrol. 2021 Dec 1;32(12):3146-3160. doi: 10.1681/ASN.2021040503. Epub 2021 Dec 1. J Am Soc Nephrol. 2021. PMID: 34588185 Free PMC article.
Adult human kidney organoids originate from CD24+ cells and represent an advanced model for adult polycystic kidney disease.
Xu Y, Kuppe C, Perales-Patón J, Hayat S, Kranz J, Abdallah AT, Nagai J, Li Z, Peisker F, Saritas T, Halder M, Menzel S, Hoeft K, Kenter A, Kim H, van Roeyen CRC, Lehrke M, Moellmann J, Speer T, Buhl EM, Hoogenboezem R, Boor P, Jansen J, Knopp C, Kurth I, Smeets B, Bindels E, Reinders MEJ, Baan C, Gribnau J, Hoorn EJ, Steffens J, Huber TB, Costa I, Floege J, Schneider RK, Saez-Rodriguez J, Freedman BS, Kramann R. Xu Y, et al. Among authors: kramann r. Nat Genet. 2022 Nov;54(11):1690-1701. doi: 10.1038/s41588-022-01202-z. Epub 2022 Oct 27. Nat Genet. 2022. PMID: 36303074 Free PMC article.
Targeting Immune-Fibroblast Crosstalk in Myocardial Infarction and Cardiac Fibrosis.
Amrute JM, Luo X, Penna V, Bredemeyer A, Yamawaki T, Yang S, Kadyrov F, Heo GS, Shi SY, Lee P, Koenig AL, Kuppe C, Jones C, Kopecky B, Hayat S, Ma P, Terada Y, Fu A, Furtado M, Kreisel D, Stitziel NO, Li CM, Kramann R, Liu Y, Ason B, Lavine KJ. Amrute JM, et al. Among authors: kramann r. Res Sq [Preprint]. 2023 Jan 26:rs.3.rs-2402606. doi: 10.21203/rs.3.rs-2402606/v1. Res Sq. 2023. PMID: 36747878 Free PMC article. Preprint.
Platelet-instructed SPP1+ macrophages drive myofibroblast activation in fibrosis in a CXCL4-dependent manner.
Hoeft K, Schaefer GJL, Kim H, Schumacher D, Bleckwehl T, Long Q, Klinkhammer BM, Peisker F, Koch L, Nagai J, Halder M, Ziegler S, Liehn E, Kuppe C, Kranz J, Menzel S, Costa I, Wahida A, Boor P, Schneider RK, Hayat S, Kramann R. Hoeft K, et al. Among authors: kramann r. Cell Rep. 2023 Feb 28;42(2):112131. doi: 10.1016/j.celrep.2023.112131. Epub 2023 Feb 18. Cell Rep. 2023. PMID: 36807143 Free PMC article.
172 results