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Exploring thienothiadiazine dioxides as isosteric analogues of benzo- and pyridothiadiazine dioxides in the search of new AMPA and kainate receptor positive allosteric modulators.
Francotte P, Bay Y, Goffin E, Colson T, Lesenfants C, Dorosz J, Laulumaa S, Fraikin P, de Tullio P, Beaufour C, Botez I, Pickering DS, Frydenvang K, Danober L, Kristensen AS, Kastrup JS, Pirotte B. Francotte P, et al. Among authors: dorosz j. Eur J Med Chem. 2024 Jan 15;264:116036. doi: 10.1016/j.ejmech.2023.116036. Epub 2023 Dec 9. Eur J Med Chem. 2024. PMID: 38101041 Free article.
Development of Thiochroman Dioxide Analogues of Benzothiadiazine Dioxides as New Positive Allosteric Modulators of α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors.
Etsè KS, Dorosz J, McLain Christensen K, Thomas JY, Botez Pop I, Goffin E, Colson T, Lestage P, Danober L, Pirotte B, Kastrup JS, Francotte P. Etsè KS, et al. Among authors: dorosz j. ACS Chem Neurosci. 2021 Jul 21;12(14):2679-2692. doi: 10.1021/acschemneuro.1c00255. Epub 2021 Jul 9. ACS Chem Neurosci. 2021. PMID: 34242002
Invisible detergents for structure determination of membrane proteins by small-angle neutron scattering.
Midtgaard SR, Darwish TA, Pedersen MC, Huda P, Larsen AH, Jensen GV, Kynde SAR, Skar-Gislinge N, Nielsen AJZ, Olesen C, Blaise M, Dorosz JJ, Thorsen TS, Venskutonytė R, Krintel C, Møller JV, Frielinghaus H, Gilbert EP, Martel A, Kastrup JS, Jensen PE, Nissen P, Arleth L. Midtgaard SR, et al. FEBS J. 2018 Jan;285(2):357-371. doi: 10.1111/febs.14345. Epub 2017 Dec 30. FEBS J. 2018. PMID: 29178440 Free article.
Structure and binding properties of a cameloid nanobody raised against KDM5B.
Wiuf A, Kristensen LH, Kristensen O, Dorosz J, Jensen J, Gajhede M. Wiuf A, et al. Among authors: dorosz j. Acta Crystallogr F Struct Biol Commun. 2015 Oct;71(Pt 10):1235-41. doi: 10.1107/S2053230X1501537X. Epub 2015 Sep 23. Acta Crystallogr F Struct Biol Commun. 2015. PMID: 26457512 Free PMC article.
Molecular architecture of the Jumonji C family histone demethylase KDM5B.
Dorosz J, Kristensen LH, Aduri NG, Mirza O, Lousen R, Bucciarelli S, Mehta V, Sellés-Baiget S, Solbak SMØ, Bach A, Mesa P, Hernandez PA, Montoya G, Nguyen TTTN, Rand KD, Boesen T, Gajhede M. Dorosz J, et al. Sci Rep. 2019 Mar 11;9(1):4019. doi: 10.1038/s41598-019-40573-y. Sci Rep. 2019. PMID: 30858420 Free PMC article.
67 results