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Comprehensive mapping of cell fates in microsatellite unstable cancer cells support dual targe6ng of WRN and ATR.
Zong D, Koussa NC, Cornwell JA, Pankajam AV, Kruhlak MJ, Wong N, Chari R, Cappell SD, Nussenzweig A. Zong D, et al. Among authors: kruhlak mj. bioRxiv [Preprint]. 2023 Jul 30:2023.07.28.550976. doi: 10.1101/2023.07.28.550976. bioRxiv. 2023. Update in: Genes Dev. 2023 Oct 1;37(19-20):913-928. doi: 10.1101/gad.351085.123. PMID: 37662356 Free PMC article. Updated. Preprint.
EWSR1's visual modalities are defined by its association with nucleic acids and RNA polymerase II.
Rajan SS, Ebegboni VJ, Pichling P, Ludwig KR, Jones TL, Chari R, Tran A, Kruhlak MJ, Loncarek J, Caplen NJ. Rajan SS, et al. Among authors: kruhlak mj. bioRxiv [Preprint]. 2023 Aug 16:2023.08.16.553246. doi: 10.1101/2023.08.16.553246. bioRxiv. 2023. Update in: Mol Cell Biol. 2024;44(3):103-122. doi: 10.1080/10985549.2024.2315425. PMID: 37645932 Free PMC article. Updated. Preprint.
AGO2 silences mobile transposons in the nucleus of quiescent cells.
Sala L, Kumar M, Prajapat M, Chandrasekhar S, Cosby RL, La Rocca G, Macfarlan TS, Awasthi P, Chari R, Kruhlak M, Vidigal JA. Sala L, et al. Among authors: kruhlak m. Nat Struct Mol Biol. 2023 Dec;30(12):1985-1995. doi: 10.1038/s41594-023-01151-z. Epub 2023 Nov 20. Nat Struct Mol Biol. 2023. PMID: 37985687
Self-organized yolk sac-like organoids allow for scalable generation of multipotent hematopoietic progenitor cells from induced pluripotent stem cells.
Tamaoki N, Siebert S, Maeda T, Ha NH, Good ML, Huang Y, Vodnala SK, Haro-Mora JJ, Uchida N, Tisdale JF, Sweeney CL, Choi U, Brault J, Koontz S, Malech HL, Yamazaki Y, Isonaka R, Goldstein DS, Kimura M, Takebe T, Zou J, Stroncek DF, Robey PG, Kruhlak MJ, Restifo NP, Vizcardo R. Tamaoki N, et al. Among authors: kruhlak mj. Cell Rep Methods. 2023 Apr 24;3(4):100460. doi: 10.1016/j.crmeth.2023.100460. eCollection 2023 Apr 24. Cell Rep Methods. 2023. PMID: 37159663 Free PMC article.
118 results