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KRAS-mediated upregulation of CIP2A promotes suppression of PP2A-B56α to initiate pancreatic cancer development.
Tinsley SL, Shelley RA, Mall GK, Chianis ERD, Dhiman A, Baral G, Kothandaraman H, Thoma MC, Daniel CJ, Lanman NA, di Magliano MP, Narla G, Solorio L, Dykhuizen EC, Sears RC, Allen-Petersen BL. Tinsley SL, et al. Among authors: sears rc. bioRxiv [Preprint]. 2024 May 23:2023.07.01.547283. doi: 10.1101/2023.07.01.547283. bioRxiv. 2024. PMID: 38826439 Free PMC article. Preprint.
Specialist physiotherapy for functional motor disorder in England and Scotland (Physio4FMD): a pragmatic, multicentre, phase 3 randomised controlled trial.
Nielsen G, Stone J, Lee TC, Goldstein LH, Marston L, Hunter RM, Carson A, Holt K, Marsden J, Le Novere M, Nazareth I, Noble H, Reuber M, Strudwick AM, Santana Suarez B, Edwards MJ; Physio4FMD study group. Nielsen G, et al. Lancet Neurol. 2024 May 16:S1474-4422(24)00135-2. doi: 10.1016/S1474-4422(24)00135-2. Online ahead of print. Lancet Neurol. 2024. PMID: 38768621 Free article.
Mutation of SIVA, a candidate metastasis gene identified from clonally related bilateral breast cancers, promotes breast cancer cell spread in vitro and in vivo.
Vermehren-Schmaedick A, Peto M, Wagoner W, Chiotti KE, Ramsey E, Wang X, Rakshe S, Minnier J, Sears R, Spellman P, Luoh SW. Vermehren-Schmaedick A, et al. Among authors: sears r. PLoS One. 2024 May 9;19(5):e0302856. doi: 10.1371/journal.pone.0302856. eCollection 2024. PLoS One. 2024. PMID: 38722955 Free PMC article.
The Pancreatic Cancer Early Detection (PRECEDE) Study is a Global Effort to Drive Early Detection: Baseline Imaging Findings in High-Risk Individuals.
Zogopoulos G, Haimi I, Sanoba SA, Everett JN, Wang Y, Katona BW, Farrell JJ, Grossberg AJ, Paiella S, Klute KA, Bi Y, Wallace MB, Kwon RS, Stoffel EM, Wadlow RC, Sussman DA, Merchant NB, Permuth JB, Golan T, Raitses-Gurevich M, Lowy AM, Liau J, Jeter JM, Lindberg JM, Chung DC, Earl J, Brentnall TA, Schrader KA, Kaul V, Huang C, Chandarana H, Smerdon C, Graff JJ, Kastrinos F, Kupfer SS, Lucas AL, Sears RC, Brand RE, Parmigiani G, Simeone DM; PRECEDE Consortium. Zogopoulos G, et al. Among authors: sears rc. J Natl Compr Canc Netw. 2024 Apr;22(3):158-166. doi: 10.6004/jnccn.2023.7097. J Natl Compr Canc Netw. 2024. PMID: 38626807
Extend the benchmarking indel set by manual review using the individual cell line sequencing data from the Sequencing Quality Control 2 (SEQC2) project.
Gong B, Li D, Zhang Y, Kusko R, Lababidi S, Cao Z, Chen M, Chen N, Chen Q, Chen Q, Dai J, Gan Q, Gao Y, Guo M, Hariani G, He Y, Hou W, Jiang H, Kushwaha G, Li JL, Li J, Li Y, Liu LC, Liu R, Liu S, Meriaux E, Mo M, Moore M, Moss TJ, Niu Q, Patel A, Ren L, Saremi NF, Shang E, Shang J, Song P, Sun S, Urban BJ, Wang D, Wang S, Wen Z, Xiong X, Yang J, Yin L, Zhang C, Zhang R, Bhandari A, Cai W, Eterovic AK, Megherbi DB, Shi T, Suo C, Yu Y, Zheng Y, Novoradovskaya N, Sears RL, Shi L, Jones W, Tong W, Xu J. Gong B, et al. Among authors: sears rl. Sci Rep. 2024 Mar 25;14(1):7028. doi: 10.1038/s41598-024-57439-7. Sci Rep. 2024. PMID: 38528062 Free PMC article.
Tuft cells transdifferentiate to neural-like progenitor cells in the progression of pancreatic cancer.
Salas-Escabillas DJ, Hoffman MT, Moore JS, Brender SM, Wen HJ, Benitz S, Davis ET, Long D, Wombwell AM, Steele NG, Sears RC, Matsumoto I, DelGiorno KE, Crawford HC. Salas-Escabillas DJ, et al. Among authors: sears rc. bioRxiv [Preprint]. 2024 Apr 23:2024.02.12.579982. doi: 10.1101/2024.02.12.579982. bioRxiv. 2024. PMID: 38405804 Free PMC article. Preprint.
301 results