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Exploring the plasticity of the InhA substrate-binding site using new diaryl ether inhibitors.
Bioorg Chem. 2024 Feb;143:107032. doi: 10.1016/j.bioorg.2023.107032. Epub 2023 Dec 12.
Bioorg Chem. 2024.
PMID: 38128204
Discovery of new diaryl ether inhibitors against Mycobacterium tuberculosis targeting the minor portal of InhA.
Chebaiki M, Delfourne E, Tamhaev R, Danoun S, Rodriguez F, Hoffmann P, Grosjean E, Goncalves F, Azéma-Despeyroux J, Pál A, Korduláková J, Preuilh N, Britton S, Constant P, Marrakchi H, Maveyraud L, Mourey L, Lherbet C.
Chebaiki M, et al.
Eur J Med Chem. 2023 Nov 5;259:115646. doi: 10.1016/j.ejmech.2023.115646. Epub 2023 Jul 16.
Eur J Med Chem. 2023.
PMID: 37482022
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Urea derivatives carrying a thiophenylthiazole moiety: Design, synthesis, and evaluation of antitubercular and InhA inhibitory activities.
Keleş Atıcı R, Doğan ŞD, Gündüz MG, Krishna VS, Chebaiki M, Homberset H, Lherbet C, Mourey L, Tønjum T.
Keleş Atıcı R, et al. Among authors: chebaiki m.
Drug Dev Res. 2022 Sep;83(6):1292-1304. doi: 10.1002/ddr.21958. Epub 2022 Jun 29.
Drug Dev Res. 2022.
PMID: 35769019
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