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In silico design, synthesis and antitubercular activity of novel 2-acylhydrazono-5-arylmethylene-4-thiazolidinones as enoyl-acyl carrier protein reductase inhibitors.
J Biomol Struct Dyn. 2024 Mar 7:1-19. doi: 10.1080/07391102.2024.2319678. Online ahead of print.
J Biomol Struct Dyn. 2024.
PMID: 38450660
Exploring the plasticity of the InhA substrate-binding site using new diaryl ether inhibitors.
Tamhaev R, Grosjean E, Ahamed H, Chebaiki M, Rodriguez F, Recchia D, Degiacomi G, Pasca MR, Maveyraud L, Mourey L, Lherbet C.
Tamhaev R, et al.
Bioorg Chem. 2024 Feb;143:107032. doi: 10.1016/j.bioorg.2023.107032. Epub 2023 Dec 12.
Bioorg Chem. 2024.
PMID: 38128204
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Discovery of new diaryl ether inhibitors against Mycobacterium tuberculosis targeting the minor portal of InhA.
Chebaiki M, Delfourne E, Tamhaev R, Danoun S, Rodriguez F, Hoffmann P, Grosjean E, Goncalves F, Azéma-Despeyroux J, Pál A, Korduláková J, Preuilh N, Britton S, Constant P, Marrakchi H, Maveyraud L, Mourey L, Lherbet C.
Chebaiki M, et al. Among authors: tamhaev r.
Eur J Med Chem. 2023 Nov 5;259:115646. doi: 10.1016/j.ejmech.2023.115646. Epub 2023 Jul 16.
Eur J Med Chem. 2023.
PMID: 37482022
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Isoniazid Linked to Sulfonate Esters via Hydrazone Functionality: Design, Synthesis, and Evaluation of Antitubercular Activity.
Koçak Aslan E, Han Mİ, Krishna VS, Tamhaev R, Dengiz C, Doğan ŞD, Lherbet C, Mourey L, Tønjum T, Gündüz MG.
Koçak Aslan E, et al. Among authors: tamhaev r.
Pharmaceuticals (Basel). 2022 Oct 21;15(10):1301. doi: 10.3390/ph15101301.
Pharmaceuticals (Basel). 2022.
PMID: 36297413
Free PMC article.
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