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Page 1
Time to drop the term 'simian malaria parasites'.
Culleton R, McFadden GI. Culleton R, et al. Among authors: mcfadden gi. Trends Parasitol. 2024 Feb;40(2):100-101. doi: 10.1016/j.pt.2023.11.010. Epub 2023 Dec 20. Trends Parasitol. 2024. PMID: 38129281
mRNA vaccine against malaria tailored for liver-resident memory T cells.
Ganley M, Holz LE, Minnell JJ, de Menezes MN, Burn OK, Poa KCY, Draper SL, English K, Chan STS, Anderson RJ, Compton BJ, Marshall AJ, Cozijnsen A, Chua YC, Ge Z, Farrand KJ, Mamum JC, Xu C, Cockburn IA, Yui K, Bertolino P, Gras S, Le Nours J, Rossjohn J, Fernandez-Ruiz D, McFadden GI, Ackerley DF, Painter GF, Hermans IF, Heath WR. Ganley M, et al. Among authors: mcfadden gi. Nat Immunol. 2023 Sep;24(9):1487-1498. doi: 10.1038/s41590-023-01562-6. Epub 2023 Jul 20. Nat Immunol. 2023. PMID: 37474653
Sulfonylpiperazine compounds prevent Plasmodium falciparum invasion of red blood cells through interference with actin-1/profilin dynamics.
Dans MG, Piirainen H, Nguyen W, Khurana S, Mehra S, Razook Z, Geoghegan ND, Dawson AT, Das S, Parkyn Schneider M, Jonsdottir TK, Gabriela M, Gancheva MR, Tonkin CJ, Mollard V, Goodman CD, McFadden GI, Wilson DW, Rogers KL, Barry AE, Crabb BS, de Koning-Ward TF, Sleebs BE, Kursula I, Gilson PR. Dans MG, et al. Among authors: mcfadden gi. PLoS Biol. 2023 Apr 13;21(4):e3002066. doi: 10.1371/journal.pbio.3002066. eCollection 2023 Apr. PLoS Biol. 2023. PMID: 37053271 Free PMC article.
Targeting malaria parasites with novel derivatives of azithromycin.
Burns AL, Sleebs BE, Gancheva M, McLean KT, Siddiqui G, Venter H, Beeson JG, O'Handley R, Creek DJ, Ma S, Frölich S, Goodman CD, McFadden GI, Wilson DW. Burns AL, et al. Among authors: mcfadden gi. Front Cell Infect Microbiol. 2022 Nov 30;12:1063407. doi: 10.3389/fcimb.2022.1063407. eCollection 2022. Front Cell Infect Microbiol. 2022. PMID: 36530422 Free PMC article.
6″-Modifed α-GalCer-peptide conjugate vaccine candidates protect against liver-stage malaria.
Meijlink MA, Chua YC, Chan STS, Anderson RJ, Rosenberg MW, Cozijnsen A, Mollard V, McFadden GI, Draper SL, Holz LE, Hermans IF, Heath WR, Painter GF, Compton BJ. Meijlink MA, et al. Among authors: mcfadden gi. RSC Chem Biol. 2022 Mar 2;3(5):551-560. doi: 10.1039/d1cb00251a. eCollection 2022 May 11. RSC Chem Biol. 2022. PMID: 35656478 Free PMC article.
Plasmodium berghei Hsp90 contains a natural immunogenic I-Ab-restricted antigen common to rodent and human Plasmodium species.
Enders MH, Bayarsaikhan G, Ghilas S, Chua YC, May R, de Menezes MN, Ge Z, Tan PS, Cozijnsen A, Mollard V, Yui K, McFadden GI, Lahoud MH, Caminschi I, Purcell AW, Schittenhelm RB, Beattie L, Heath WR, Fernandez-Ruiz D. Enders MH, et al. Among authors: mcfadden gi. Curr Res Immunol. 2021 Jun 30;2:79-92. doi: 10.1016/j.crimmu.2021.06.002. eCollection 2021. Curr Res Immunol. 2021. PMID: 35492393 Free PMC article.
Optimisation of 2-(N-phenyl carboxamide) triazolopyrimidine antimalarials with moderate to slow acting erythrocytic stage activity.
Bailey BL, Nguyen W, Ngo A, Goodman CD, Gancheva MR, Favuzza P, Sanz LM, Gamo FJ, Lowes KN, McFadden GI, Wilson DW, Laleu B, Brand S, Jackson PF, Cowman AF, Sleebs BE. Bailey BL, et al. Among authors: mcfadden gi. Bioorg Chem. 2021 Oct;115:105244. doi: 10.1016/j.bioorg.2021.105244. Epub 2021 Aug 8. Bioorg Chem. 2021. PMID: 34452759
202 results