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HKDC1, a target of TFEB, is essential to maintain both mitochondrial and lysosomal homeostasis, preventing cellular senescence.
Cui M, Yamano K, Yamamoto K, Yamamoto-Imoto H, Minami S, Yamamoto T, Matsui S, Kaminishi T, Shima T, Ogura M, Tsuchiya M, Nishino K, Layden BT, Kato H, Ogawa H, Oki S, Okada Y, Isaka Y, Kosako H, Matsuda N, Yoshimori T, Nakamura S. Cui M, et al. Among authors: isaka y. Proc Natl Acad Sci U S A. 2024 Jan 9;121(2):e2306454120. doi: 10.1073/pnas.2306454120. Epub 2024 Jan 3. Proc Natl Acad Sci U S A. 2024. PMID: 38170752
Autophagy guards against cisplatin-induced acute kidney injury.
Takahashi A, Kimura T, Takabatake Y, Namba T, Kaimori J, Kitamura H, Matsui I, Niimura F, Matsusaka T, Fujita N, Yoshimori T, Isaka Y, Rakugi H. Takahashi A, et al. Among authors: isaka y. Am J Pathol. 2012 Feb;180(2):517-25. doi: 10.1016/j.ajpath.2011.11.001. Am J Pathol. 2012. PMID: 22265049
Hyperuricemia-induced inflammasome and kidney diseases.
Isaka Y, Takabatake Y, Takahashi A, Saitoh T, Yoshimori T. Isaka Y, et al. Nephrol Dial Transplant. 2016 Jun;31(6):890-6. doi: 10.1093/ndt/gfv024. Epub 2015 Mar 31. Nephrol Dial Transplant. 2016. PMID: 25829326 Review.
Time-dependent dysregulation of autophagy: Implications in aging and mitochondrial homeostasis in the kidney proximal tubule.
Yamamoto T, Takabatake Y, Kimura T, Takahashi A, Namba T, Matsuda J, Minami S, Kaimori JY, Matsui I, Kitamura H, Matsusaka T, Niimura F, Yanagita M, Isaka Y, Rakugi H. Yamamoto T, et al. Among authors: isaka y. Autophagy. 2016 May 3;12(5):801-13. doi: 10.1080/15548627.2016.1159376. Epub 2016 Mar 17. Autophagy. 2016. PMID: 26986194 Free PMC article.
Autophagy Inhibits the Accumulation of Advanced Glycation End Products by Promoting Lysosomal Biogenesis and Function in the Kidney Proximal Tubules.
Takahashi A, Takabatake Y, Kimura T, Maejima I, Namba T, Yamamoto T, Matsuda J, Minami S, Kaimori JY, Matsui I, Matsusaka T, Niimura F, Yoshimori T, Isaka Y. Takahashi A, et al. Among authors: isaka y. Diabetes. 2017 May;66(5):1359-1372. doi: 10.2337/db16-0397. Epub 2017 Feb 28. Diabetes. 2017. PMID: 28246295
Autophagy and kidney inflammation.
Kimura T, Isaka Y, Yoshimori T. Kimura T, et al. Among authors: isaka y. Autophagy. 2017 Jun 3;13(6):997-1003. doi: 10.1080/15548627.2017.1309485. Epub 2017 Apr 25. Autophagy. 2017. PMID: 28441075 Free PMC article. Review.
537 results