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Page 1
Learning fast and fine-grained detection of amyloid neuropathologies from coarse-grained expert labels.
Wong DR, Magaki SD, Vinters HV, Yong WH, Monuki ES, Williams CK, Martini AC, DeCarli C, Khacherian C, Graff JP, Dugger BN, Keiser MJ. Wong DR, et al. Among authors: vinters hv. bioRxiv [Preprint]. 2023 Jan 17:2023.01.13.524019. doi: 10.1101/2023.01.13.524019. bioRxiv. 2023. Update in: Commun Biol. 2023 Jun 24;6(1):668. doi: 10.1038/s42003-023-05031-6. PMID: 36711704 Free PMC article. Updated. Preprint.
Improving the solubility of pseudo-hydrophobic Alzheimer's Disease medicinal chemicals through co-crystal formulation.
Tse A, Janilkarn-Urena I, Lin J, Chang X, Efthymiou C, Idrissova A, Zhang M, Williams CK, Magaki S, Vinters HV, Davies DL, Gonen T, Gukasyan HJ, Seidler PM. Tse A, et al. Among authors: vinters hv. bioRxiv [Preprint]. 2023 Apr 28:2023.04.25.538327. doi: 10.1101/2023.04.25.538327. bioRxiv. 2023. PMID: 37162961 Free PMC article. Preprint.
Author Correction: Post-translational modifications of soluble α-synuclein regulate the amplification of pathological α-synuclein.
Zhang S, Zhu R, Pan B, Xu H, Olufemi MF, Gathagan RJ, Li Y, Zhang L, Zhang J, Xiang W, Kagan EM, Cao X, Yuan C, Kim SJ, Williams CK, Magaki S, Vinters HV, Lashuel HA, Garcia BA, James Petersson E, Trojanowski JQ, Lee VM, Peng C. Zhang S, et al. Among authors: vinters hv. Nat Neurosci. 2023 Dec;26(12):2250. doi: 10.1038/s41593-023-01474-6. Nat Neurosci. 2023. PMID: 37814027 No abstract available.
HIV and COVID-19: two pandemics with significant (but different) central nervous system complications.
Magaki S, Zhang T, Han K, Hilda M, Yong WH, Achim C, Fishbein G, Fishbein MC, Garner O, Salamon N, Williams CK, Valdes-Sueiras MA, Hsu JJ, Kelesidis T, Mathisen GE, Lavretsky H, Singer EJ, Vinters HV. Magaki S, et al. Among authors: vinters hv. Free Neuropathol. 2024 Mar 5;5:5-5. doi: 10.17879/freeneuropathology-2024-5343. eCollection 2024 Jan. Free Neuropathol. 2024. PMID: 38469363 Free PMC article.
Intercellular Signaling Pathways as Therapeutic Targets for Vascular Dementia Repair.
Tian M, Kawaguchi R, Shen Y, Machnicki M, Villegas NG, Cooper DR, Montgomery N, Haring J, Lan R, Yuan AH, Williams CK, Magaki S, Vinters HV, Zhang Y, De Biase LM, Silva AJ, Carmichael ST. Tian M, et al. Among authors: vinters hv. bioRxiv [Preprint]. 2024 Mar 27:2024.03.24.585301. doi: 10.1101/2024.03.24.585301. bioRxiv. 2024. PMID: 38585718 Free PMC article. Preprint.
Structure-based design of nanobodies that inhibit seeding of Alzheimer's patient-extracted tau fibrils.
Abskharon R, Pan H, Sawaya MR, Seidler PM, Olivares EJ, Chen Y, Murray KA, Zhang J, Lantz C, Bentzel M, Boyer DR, Cascio D, Nguyen BA, Hou K, Cheng X, Pardon E, Williams CK, Nana AL, Vinters HV, Spina S, Grinberg LT, Seeley WW, Steyaert J, Glabe CG, Ogorzalek Loo RR, Loo JA, Eisenberg DS. Abskharon R, et al. Among authors: vinters hv. Proc Natl Acad Sci U S A. 2023 Oct 10;120(41):e2300258120. doi: 10.1073/pnas.2300258120. Epub 2023 Oct 6. Proc Natl Acad Sci U S A. 2023. PMID: 37801475 Free PMC article.
Sex-specific genetic predictors of Alzheimer's disease biomarkers.
Deming Y, Dumitrescu L, Barnes LL, Thambisetty M, Kunkle B, Gifford KA, Bush WS, Chibnik LB, Mukherjee S, De Jager PL, Kukull W, Huentelman M, Crane PK, Resnick SM, Keene CD, Montine TJ, Schellenberg GD, Haines JL, Zetterberg H, Blennow K, Larson EB, Johnson SC, Albert M, Moghekar A, Del Aguila JL, Fernandez MV, Budde J, Hassenstab J, Fagan AM, Riemenschneider M, Petersen RC, Minthon L, Chao MJ, Van Deerlin VM, Lee VM, Shaw LM, Trojanowski JQ, Peskind ER, Li G, Davis LK, Sealock JM, Cox NJ; Alzheimer’s Disease Neuroimaging Initiative (ADNI); Alzheimer Disease Genetics Consortium (ADGC); Goate AM, Bennett DA, Schneider JA, Jefferson AL, Cruchaga C, Hohman TJ. Deming Y, et al. Acta Neuropathol. 2018 Dec;136(6):857-872. doi: 10.1007/s00401-018-1881-4. Epub 2018 Jul 2. Acta Neuropathol. 2018. PMID: 29967939 Free PMC article.
Disease-specific selective vulnerability and neuroimmune pathways in dementia revealed by single cell genomics.
Rexach JE, Cheng Y, Chen L, Polioudakis D, Lin LC, Mitri V, Elkins A, Yin A, Calini D, Kawaguchi R, Ou J, Huang J, Williams C, Robinson J, Gaus SE, Spina S, Lee EB, Grinberg LT, Vinters H, Trojanowski JQ, Seeley WW, Malhotra D, Geschwind DH. Rexach JE, et al. bioRxiv [Preprint]. 2023 Sep 30:2023.09.29.560245. doi: 10.1101/2023.09.29.560245. bioRxiv. 2023. PMID: 37808727 Free PMC article. Preprint.
588 results