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Combined inhibition of Wee1 and Chk1 as a therapeutic strategy in multiple myeloma.
Bruyer A, Dutrieux L, de Boussac H, Martin T, Chemlal D, Robert N, Requirand G, Cartron G, Vincent L, Herbaux C, Lutzmann M, Bret C, Pasero P, Moreaux J, Ovejero S. Bruyer A, et al. Among authors: pasero p. Front Oncol. 2023 Dec 6;13:1271847. doi: 10.3389/fonc.2023.1271847. eCollection 2023. Front Oncol. 2023. PMID: 38125947 Free PMC article.
The BLM helicase is a new therapeutic target in multiple myeloma involved in replication stress survival and drug resistance.
Ovejero S, Viziteu E, Dutrieux L, Devin J, Lin YL, Alaterre E, Jourdan M, Basbous J, Requirand G, Robert N, de Boussac H, Seckinger A, Hose D, Vincent L, Herbaux C, Constantinou A, Pasero P, Moreaux J. Ovejero S, et al. Among authors: pasero p. Front Immunol. 2022 Dec 9;13:983181. doi: 10.3389/fimmu.2022.983181. eCollection 2022. Front Immunol. 2022. PMID: 36569948 Free PMC article.
Angiotensin II induces reactive oxygen species, DNA damage, and T-cell apoptosis in severe COVID-19.
Kundura L, Gimenez S, Cezar R, André S, Younas M, Lin YL, Portalès P, Lozano C, Boulle C, Reynes J, Vincent T, Mettling C, Pasero P, Muller L, Lefrant JY, Roger C, Claret PG, Duvnjak S, Loubet P, Sotto A, Tran TA, Estaquier J, Corbeau P. Kundura L, et al. Among authors: pasero p. J Allergy Clin Immunol. 2022 Sep;150(3):594-603.e2. doi: 10.1016/j.jaci.2022.06.020. Epub 2022 Jul 14. J Allergy Clin Immunol. 2022. PMID: 35841981 Free PMC article.
Sen1 is a key regulator of transcription-driven conflicts.
Aiello U, Challal D, Wentzinger G, Lengronne A, Appanah R, Pasero P, Palancade B, Libri D. Aiello U, et al. Among authors: pasero p. Mol Cell. 2022 Aug 18;82(16):2952-2966.e6. doi: 10.1016/j.molcel.2022.06.021. Epub 2022 Jul 14. Mol Cell. 2022. PMID: 35839782 Free article.
127 results