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Antibody Isotypes for Tumor Immunotherapy.
Kretschmer A, Schwanbeck R, Valerius T, Rösner T. Kretschmer A, et al. Among authors: schwanbeck r. Transfus Med Hemother. 2017 Sep;44(5):320-326. doi: 10.1159/000479240. Epub 2017 Sep 7. Transfus Med Hemother. 2017. PMID: 29070977 Free PMC article. Review.
Effector mechanisms of IgA antibodies against CD20 include recruitment of myeloid cells for antibody-dependent cell-mediated cytotoxicity and complement-dependent cytotoxicity.
Lohse S, Loew S, Kretschmer A, Jansen JHM, Meyer S, Ten Broeke T, Rösner T, Dechant M, Derer S, Klausz K, Kellner C, Schwanbeck R, French RR, Tipton TRW, Cragg MS, Schewe DM, Peipp M, Leusen JHW, Valerius T. Lohse S, et al. Among authors: schwanbeck r. Br J Haematol. 2018 May;181(3):413-417. doi: 10.1111/bjh.14624. Epub 2017 Apr 27. Br J Haematol. 2018. PMID: 28449349 Free article. No abstract available.
Monoclonal Antibodies against Epidermal Growth Factor Receptor Acquire an Ability To Kill Tumor Cells through Complement Activation by Mutations That Selectively Facilitate the Hexamerization of IgG on Opsonized Cells.
Tammen A, Derer S, Schwanbeck R, Rösner T, Kretschmer A, Beurskens FJ, Schuurman J, Parren PW, Valerius T. Tammen A, et al. Among authors: schwanbeck r. J Immunol. 2017 Feb 15;198(4):1585-1594. doi: 10.4049/jimmunol.1601268. Epub 2017 Jan 6. J Immunol. 2017. PMID: 28062698
The amino acid exchange R28E in ciliary neurotrophic factor (CNTF) abrogates interleukin-6 receptor-dependent but retains CNTF receptor-dependent signaling via glycoprotein 130 (gp130)/leukemia inhibitory factor receptor (LIFR).
Wagener EM, Aurich M, Aparicio-Siegmund S, Floss DM, Garbers C, Breusing K, Rabe B, Schwanbeck R, Grötzinger J, Rose-John S, Scheller J. Wagener EM, et al. Among authors: schwanbeck r. J Biol Chem. 2014 Jun 27;289(26):18442-50. doi: 10.1074/jbc.M114.568857. Epub 2014 May 6. J Biol Chem. 2014. PMID: 24802752 Free PMC article.
37 results