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A spatial cell atlas of neuroblastoma reveals developmental, epigenetic and spatial axis of tumor heterogeneity.
Patel AG, Ashenberg O, Collins NB, Segerstolpe Å, Jiang S, Slyper M, Huang X, Caraccio C, Jin H, Sheppard H, Xu K, Chang TC, Orr BA, Shirinifard A, Chapple RH, Shen A, Clay MR, Tatevossian RG, Reilly C, Patel J, Lupo M, Cline C, Dionne D, Porter CBM, Waldman J, Bai Y, Zhu B, Barrera I, Murray E, Vigneau S, Napolitano S, Wakiro I, Wu J, Grimaldi G, Dellostritto L, Helvie K, Rotem A, Lako A, Cullen N, Pfaff KL, Karlström Å, Jané-Valbuena J, Todres E, Thorner A, Geeleher P, Rodig SJ, Zhou X, Stewart E, Johnson BE, Wu G, Chen F, Yu J, Goltsev Y, Nolan GP, Rozenblatt-Rosen O, Regev A, Dyer MA. Patel AG, et al. Among authors: chen f. bioRxiv [Preprint]. 2024 Jan 16:2024.01.07.574538. doi: 10.1101/2024.01.07.574538. bioRxiv. 2024. PMID: 38260392 Free PMC article. Preprint.
The cell type composition of the adult mouse brain revealed by single cell and spatial genomics.
Langlieb J, Sachdev NS, Balderrama KS, Nadaf NM, Raj M, Murray E, Webber JT, Vanderburg C, Gazestani V, Tward D, Mezias C, Li X, Cable DM, Norton T, Mitra P, Chen F, Macosko EZ. Langlieb J, et al. Among authors: chen f. bioRxiv [Preprint]. 2023 Mar 13:2023.03.06.531307. doi: 10.1101/2023.03.06.531307. bioRxiv. 2023. PMID: 36945580 Free PMC article. Preprint.
Plasmodium infection induces phenotypic, clonal, and spatial diversity among differentiating CD4+ T cells.
Williams CG, Moreira ML, Asatsuma T, Lee HJ, Li S, Barrera I, Murray E, Soon MSF, Engel JA, Khoury DS, Le S, Wanrooy BJ, Schienstock D, Alexandre YO, Skinner OP, Joseph R, Beattie L, Mueller SN, Chen F, Haque A. Williams CG, et al. Among authors: chen f. Cell Rep. 2024 Jun 5;43(6):114317. doi: 10.1016/j.celrep.2024.114317. Online ahead of print. Cell Rep. 2024. PMID: 38848213 Free article.
Disease-associated astrocytes in Alzheimer's disease and aging.
Habib N, McCabe C, Medina S, Varshavsky M, Kitsberg D, Dvir-Szternfeld R, Green G, Dionne D, Nguyen L, Marshall JL, Chen F, Zhang F, Kaplan T, Regev A, Schwartz M. Habib N, et al. Among authors: chen f. Nat Neurosci. 2020 Jun;23(6):701-706. doi: 10.1038/s41593-020-0624-8. Epub 2020 Apr 27. Nat Neurosci. 2020. PMID: 32341542 Free PMC article.
Expansion sequencing: Spatially precise in situ transcriptomics in intact biological systems.
Alon S, Goodwin DR, Sinha A, Wassie AT, Chen F, Daugharthy ER, Bando Y, Kajita A, Xue AG, Marrett K, Prior R, Cui Y, Payne AC, Yao CC, Suk HJ, Wang R, Yu CJ, Tillberg P, Reginato P, Pak N, Liu S, Punthambaker S, Iyer EPR, Kohman RE, Miller JA, Lein ES, Lako A, Cullen N, Rodig S, Helvie K, Abravanel DL, Wagle N, Johnson BE, Klughammer J, Slyper M, Waldman J, Jané-Valbuena J, Rozenblatt-Rosen O, Regev A; IMAXT Consortium; Church GM, Marblestone AH, Boyden ES. Alon S, et al. Among authors: chen f. Science. 2021 Jan 29;371(6528):eaax2656. doi: 10.1126/science.aax2656. Science. 2021. PMID: 33509999 Free PMC article.
Robust decomposition of cell type mixtures in spatial transcriptomics.
Cable DM, Murray E, Zou LS, Goeva A, Macosko EZ, Chen F, Irizarry RA. Cable DM, et al. Among authors: chen f. Nat Biotechnol. 2022 Apr;40(4):517-526. doi: 10.1038/s41587-021-00830-w. Epub 2021 Feb 18. Nat Biotechnol. 2022. PMID: 33603203 Free PMC article.
Compressed sensing for highly efficient imaging transcriptomics.
Cleary B, Simonton B, Bezney J, Murray E, Alam S, Sinha A, Habibi E, Marshall J, Lander ES, Chen F, Regev A. Cleary B, et al. Among authors: chen f. Nat Biotechnol. 2021 Aug;39(8):936-942. doi: 10.1038/s41587-021-00883-x. Epub 2021 Apr 15. Nat Biotechnol. 2021. PMID: 33859401 Free PMC article.
Joint single-cell measurements of nuclear proteins and RNA in vivo.
Chung H, Parkhurst CN, Magee EM, Phillips D, Habibi E, Chen F, Yeung BZ, Waldman J, Artis D, Regev A. Chung H, et al. Among authors: chen f. Nat Methods. 2021 Oct;18(10):1204-1212. doi: 10.1038/s41592-021-01278-1. Epub 2021 Oct 4. Nat Methods. 2021. PMID: 34608310 Free PMC article.
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