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Genetic and multi-omic risk assessment of Alzheimer's disease implicates core associated biological domains.
Cary GA, Wiley JC, Gockley J, Keegan S, Amirtha Ganesh SS, Heath L, Butler RR 3rd, Mangravite LM, Logsdon BA, Longo FM, Levey A, Greenwood AK, Carter GW. Cary GA, et al. Among authors: gockley j. Alzheimers Dement (N Y). 2024 Apr 22;10(2):e12461. doi: 10.1002/trc2.12461. eCollection 2024 Apr-Jun. Alzheimers Dement (N Y). 2024. PMID: 38650747 Free PMC article.
Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM.
Bashore FM, Katis VL, Du Y, Sikdar A, Wang D, Bradshaw WJ, Rygiel KA, Leisner TM, Chalk R, Mishra S, Williams CA, Gileadi O, Brennan PE, Wiley JC, Gockley J, Cary GA, Carter GW, Young JE, Pearce KH, Fu H; Emory-Sage-SGC TREAT-AD Center; Axtman AD. Bashore FM, et al. Among authors: gockley j. PLoS One. 2024 Feb 15;19(2):e0293548. doi: 10.1371/journal.pone.0293548. eCollection 2024. PLoS One. 2024. PMID: 38359047 Free PMC article.
Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM.
Bashore FM, Katis VL, Du Y, Sikdar A, Wang D, Bradshaw WJ, Rygiel KA, Leisner TM, Chalk R, Mishra S, Williams AC, Gileadi O, Brennan PE, Wiley JC, Gockley J, Cary GA, Carter GW, Young JE, Pearce KH, Fu H; Emory-Sage-SGC TREAT-AD Center; Axtman AD. Bashore FM, et al. Among authors: gockley j. bioRxiv [Preprint]. 2023 Jul 29:2023.07.28.551026. doi: 10.1101/2023.07.28.551026. bioRxiv. 2023. Update in: PLoS One. 2024 Feb 15;19(2):e0293548. doi: 10.1371/journal.pone.0293548. PMID: 37547005 Free PMC article. Updated. Preprint.
Integrating human brain proteomes with genome-wide association data implicates novel proteins in post-traumatic stress disorder.
Wingo TS, Gerasimov ES, Liu Y, Duong DM, Vattathil SM, Lori A, Gockley J, Breen MS, Maihofer AX, Nievergelt CM, Koenen KC, Levey DF, Gelernter J, Stein MB, Ressler KJ, Bennett DA, Levey AI, Seyfried NT, Wingo AP. Wingo TS, et al. Among authors: gockley j. Mol Psychiatry. 2022 Jul;27(7):3075-3084. doi: 10.1038/s41380-022-01544-4. Epub 2022 Apr 21. Mol Psychiatry. 2022. PMID: 35449297 Free PMC article.
Brain proteome-wide association study implicates novel proteins in depression pathogenesis.
Wingo TS, Liu Y, Gerasimov ES, Gockley J, Logsdon BA, Duong DM, Dammer EB, Lori A, Kim PJ, Ressler KJ, Beach TG, Reiman EM, Epstein MP, De Jager PL, Lah JJ, Bennett DA, Seyfried NT, Levey AI, Wingo AP. Wingo TS, et al. Among authors: gockley j. Nat Neurosci. 2021 Jun;24(6):810-817. doi: 10.1038/s41593-021-00832-6. Epub 2021 Apr 12. Nat Neurosci. 2021. PMID: 33846625 Free PMC article.
Integrating human brain proteomes with genome-wide association data implicates new proteins in Alzheimer's disease pathogenesis.
Wingo AP, Liu Y, Gerasimov ES, Gockley J, Logsdon BA, Duong DM, Dammer EB, Robins C, Beach TG, Reiman EM, Epstein MP, De Jager PL, Lah JJ, Bennett DA, Seyfried NT, Levey AI, Wingo TS. Wingo AP, et al. Among authors: gockley j. Nat Genet. 2021 Feb;53(2):143-146. doi: 10.1038/s41588-020-00773-z. Epub 2021 Jan 28. Nat Genet. 2021. PMID: 33510477 Free PMC article.
Bone marrow microenvironments that contribute to patient outcomes in newly diagnosed multiple myeloma: A cohort study of patients in the Total Therapy clinical trials.
Danziger SA, McConnell M, Gockley J, Young MH, Rosenthal A, Schmitz F, Reiss DJ, Farmer P, Alapat DV, Singh A, Ashby C, Bauer M, Ren Y, Smith K, Couto SS, van Rhee F, Davies F, Zangari M, Petty N, Orlowski RZ, Dhodapkar MV, Copeland WB, Fox B, Hoering A, Fitch A, Newhall K, Barlogie B, Trotter MWB, Hershberg RM, Walker BA, Dervan AP, Ratushny AV, Morgan GJ. Danziger SA, et al. Among authors: gockley j. PLoS Med. 2020 Nov 4;17(11):e1003323. doi: 10.1371/journal.pmed.1003323. eCollection 2020 Nov. PLoS Med. 2020. PMID: 33147277 Free PMC article. Clinical Trial.
15 results