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Unveiling the phytochemical profile, antioxidant and antibacterial activities, acute toxicity insight and analgesic effect of Retama dasycarpa stems: An unexplored endemic plant from Morocco.
El Baakili A, Fadil M, Guaouguaou FE, Missbah El Idrissi M, Taghzouti K, Jeddi M, Fikri-Benbrahim K, Es-Safi NE. El Baakili A, et al. Heliyon. 2024 Sep 6;10(18):e37429. doi: 10.1016/j.heliyon.2024.e37429. eCollection 2024 Sep 30. Heliyon. 2024. PMID: 39309869 Free PMC article.
Effect of pioglitazone on inflammatory response and clinical outcome in T2DM patients with COVID-19: a randomized multicenter double-blind clinical trial.
Baagar K, Alessa T, Abu-Farha M, Abubaker J, Alhumaidi H, Franco Ceruto JA, Hamad MK, Omrani A, Abdelrahman S, Zaka-Ul Haq M, Safi AW, Alhariri B, Barman M, Abdelmajid A, Cancio HVD, Elmekaty E, Al-Khairi I, Cherian P, Jayyousi L, Ahmed M, Qaddoumi M, Hajji S, Esmaeel A, Al-Andaleeb A, Channanath A, Devarajan S, Ali H, Thanaraj TA, Al-Sabah S, Al-Mulla F, Abdul-Ghani M, Jayyousi A. Baagar K, et al. Front Immunol. 2024 Sep 6;15:1369918. doi: 10.3389/fimmu.2024.1369918. eCollection 2024. Front Immunol. 2024. PMID: 39308871 Free PMC article. Clinical Trial.
Treatment with pioglitazone showed a significant reduction in interleukin (IL)-3 levels compared with placebo treatment (mean (SD) 2.73 ( 2.14) [95% CI: 0.02, 1.1], p = 0.043 vs. 2.28 ( 1.67) [95% CI: - 0.23, 0.86], p = 0.3, respectively), with no effect seen in the …
Treatment with pioglitazone showed a significant reduction in interleukin (IL)-3 levels compared with placebo treatment (mean (SD) 2.73 ( 2. …
Phytochemical Diversity and Biological Effects of Juniperus thurifera L., Essential Oil : A Comparative Study using In Vitro and In Silico Methods.
Elhrech H, Aguerd O, El Omari N, Benali T, Akhazzane M, Alotaibi A, Ullah R, Chamkhi I, Bouyahya A. Elhrech H, et al. Chem Biodivers. 2024 Sep 12:e202401654. doi: 10.1002/cbdv.202401654. Online ahead of print. Chem Biodivers. 2024. PMID: 39266453
In silico analyses of six target enzymes confirmed significant binding affinities of the major compounds. Notably, 2,2'-Thiobis(6-tert-butyl-p-cresol) exhibited strong binding affinities with AChE, BChE, alpha-amylase, alpha-glucosidase, tyrosinase, and elastase, with bind …
In silico analyses of six target enzymes confirmed significant binding affinities of the major compounds. Notably, 2,2'-Thiobis(6-tert-butyl …
Impact of Surgical Strategy and Post-Repair Transverse Aortic Arch Size on Late Hypertension After Coarctation Repair During Infancy.
Safi S, Hoganson D, Emani S, Sleeper L, Elia E, Lu M, Biering-Sørensen T, Prakash A. Safi S, et al. J Thorac Cardiovasc Surg. 2024 Sep 6:S0022-5223(24)00783-9. doi: 10.1016/j.jtcvs.2024.08.049. Online ahead of print. J Thorac Cardiovasc Surg. 2024. PMID: 39245406
After controlling for age at repair, gender, and presence of a genetic syndrome, HTN was not associated with immediate post-repair TAA diameter z-score, (p=0.41), type of surgical incision (p=0.99), or type of surgical repair (p=0.66). CONCLUSIONS: In patient …
After controlling for age at repair, gender, and presence of a genetic syndrome, HTN was not associated with immediate post-repair TAA diame …
An Investigation of Novel Series of 2-Thioxo-1,3-dithiol-carboxamides as Potential Antispasmodic Agents: Design, Synthesis via Coupling Reactions, Density Functional Theory Calculations, and Molecular Docking.
Sghyar R, Lahyaoui M, Aflak N, Moussaoui O, Chda A, Bencheikh R, El Hadrami EM, Sebbar NK, Alanazi AS, Hefnawy M. Sghyar R, et al. Molecules. 2024 Aug 14;29(16):3855. doi: 10.3390/molecules29163855. Molecules. 2024. PMID: 39202934 Free PMC article.
A DFT computational study at the B3LYP/6-31G(d,p) level was conducted on the four synthesized compounds to compare their electronic properties and molecular structures. ...
A DFT computational study at the B3LYP/6-31G(d,p) level was conducted on the four synthesized compounds to compare their electronic p …
Lateral versus supine position for tracheal extubation among infants after intraabdominal surgery: A randomised controlled trial.
Jarraya A, Kammoun M, Bouchaira H, Ketata H, Safi F, Ben Hamad A. Jarraya A, et al. J Perioper Pract. 2024 Aug 12:17504589241261184. doi: 10.1177/17504589241261184. Online ahead of print. J Perioper Pract. 2024. PMID: 39133162
The incidence of perioperative respiratory adverse events after tracheal extubation was 21.6% and 5% in the supine and lateral position groups, respectively, with p = 0.007 and odds ratio = 3.87; 95% confidence interval: 1.18-12.6. Lateral position also reduced the inciden …
The incidence of perioperative respiratory adverse events after tracheal extubation was 21.6% and 5% in the supine and lateral position grou …
Peri- and postoperative morbidity and mortality in older patients with non-small cell lung cancer: a matched-pair study.
Safi S, Gysan MR, Weber D, Behnisch R, Muley T, Allgäuer M, Winter H, Hoffmann H, Eichhorn M. Safi S, et al. World J Surg Oncol. 2024 Aug 8;22(1):213. doi: 10.1186/s12957-024-03491-6. World J Surg Oncol. 2024. PMID: 39118130 Free PMC article.
RESULTS: 454 patients were included in the matched-pair analysis. 36% of younger patients developed postoperative complications versus 42% in older patients (p = 0.163). Age was not significantly associated with the occurrence of postoperative complications. Median length …
RESULTS: 454 patients were included in the matched-pair analysis. 36% of younger patients developed postoperative complications versus 42% i …
Association between serum hormone levels in early pregnancy and risk of hypertensive diseases of pregnancy in women undergoing assisted reproduction.
Martel RA, Lee V, Armstrong A, Demirjian M, Kwan L, Al-Safi ZA. Martel RA, et al. J Assist Reprod Genet. 2024 Sep;41(9):2359-2366. doi: 10.1007/s10815-024-03212-8. Epub 2024 Jul 25. J Assist Reprod Genet. 2024. PMID: 39052170 Free PMC article.

While median levels of E2 and P4 were significantly different between P-FET and NC-FET patients (E2: 252 vs 317 pg/mL, P4: 64 vs 29 ng/mL, respectively; both p < 0.01), rates of hypertensive diseases of pregnancy did not significantly differ between those two gro

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While median levels of E2 and P4 were significantly different between P-FET and NC-FET patients (E2: 252 vs 317 pg/mL, P4: 64 vs 29 n …
658 results