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Design, synthesis, and molecular modeling studies of novel 2-quinolone-1,2,3-triazole-α-aminophosphonates hybrids as dual antiviral and antibacterial agents.
Gadali KE, Rafya M, El Mansouri AE, Maatallah M, Vanderlee A, Mehdi A, Neyts J, Jochmans D, De Jonghe S, Benkhalti F, Sanghvi YS, Taourirte M, Lazrek HB. Gadali KE, et al. Among authors: jochmans d. Eur J Med Chem. 2024 Mar 15;268:116235. doi: 10.1016/j.ejmech.2024.116235. Epub 2024 Feb 16. Eur J Med Chem. 2024. PMID: 38377828 Review.
TMC114, a novel human immunodeficiency virus type 1 protease inhibitor active against protease inhibitor-resistant viruses, including a broad range of clinical isolates.
De Meyer S, Azijn H, Surleraux D, Jochmans D, Tahri A, Pauwels R, Wigerinck P, de Béthune MP. De Meyer S, et al. Among authors: jochmans d. Antimicrob Agents Chemother. 2005 Jun;49(6):2314-21. doi: 10.1128/AAC.49.6.2314-2321.2005. Antimicrob Agents Chemother. 2005. PMID: 15917527 Free PMC article.
Resistance mutations in human immunodeficiency virus type 1 integrase selected with elvitegravir confer reduced susceptibility to a wide range of integrase inhibitors.
Goethals O, Clayton R, Van Ginderen M, Vereycken I, Wagemans E, Geluykens P, Dockx K, Strijbos R, Smits V, Vos A, Meersseman G, Jochmans D, Vermeire K, Schols D, Hallenberger S, Hertogs K. Goethals O, et al. Among authors: jochmans d. J Virol. 2008 Nov;82(21):10366-74. doi: 10.1128/JVI.00470-08. Epub 2008 Aug 20. J Virol. 2008. PMID: 18715920 Free PMC article.
106 results