Govindan SV - Search Results

1

Sacituzumab govitecan plus platinum-based chemotherapy mediates significant antitumor effects in triple-negative breast, urinary bladder, and small-cell lung carcinomas.

Cardillo TM, Zalath MB, Arrojo R, Sharkey RM, Govindan SV, Chang CH, Goldenberg DM. Cardillo TM, et al. Among authors: govindan sv. Oncotarget. 2024 Feb 22;15:144-158. doi: 10.18632/oncotarget.28559. Oncotarget. 2024. PMID: 38386805 Free PMC article.

2

Trop-2 is a novel target for solid cancer therapy with sacituzumab govitecan (IMMU-132), an antibody-drug conjugate (ADC).

Goldenberg DM, Cardillo TM, Govindan SV, Rossi EA, Sharkey RM. Goldenberg DM, et al. Among authors: govindan sv. Oncotarget. 2015 Sep 8;6(26):22496-512. doi: 10.18632/oncotarget.4318. Oncotarget. 2015. PMID: 26101915 Free PMC article.

3

Correction: Trop-2 is a novel target for solid cancer therapy with sacituzumab govitecan (IMMU-132), an antibody-drug conjugate (ADC).

Goldenberg DM, Cardillo TM, Govindan SV, Rossi EA, Sharkey RM. Goldenberg DM, et al. Among authors: govindan sv. Oncotarget. 2020 Mar 10;11(10):942. doi: 10.18632/oncotarget.27512. eCollection 2020 Mar 10. Oncotarget. 2020. PMID: 32206190 Free PMC article.

4

New antibody conjugates in cancer therapy.

Govindan SV, Goldenberg DM. Govindan SV, et al. ScientificWorldJournal. 2010 Oct 12;10:2070-89. doi: 10.1100/tsw.2010.191. ScientificWorldJournal. 2010. PMID: 20953556 Free PMC article. Review.

5

Humanized anti-Trop-2 IgG-SN-38 conjugate for effective treatment of diverse epithelial cancers: preclinical studies in human cancer xenograft models and monkeys.

Cardillo TM, Govindan SV, Sharkey RM, Trisal P, Goldenberg DM. Cardillo TM, et al. Among authors: govindan sv. Clin Cancer Res. 2011 May 15;17(10):3157-69. doi: 10.1158/1078-0432.CCR-10-2939. Epub 2011 Mar 3. Clin Cancer Res. 2011. PMID: 21372224 Free PMC article.

6

Combination radioimmunotherapy and chemoimmunotherapy involving different or the same targets improves therapy of human pancreatic carcinoma xenograft models.

Sharkey RM, Karacay H, Govindan SV, Goldenberg DM. Sharkey RM, et al. Among authors: govindan sv. Mol Cancer Ther. 2011 Jun;10(6):1072-81. doi: 10.1158/1535-7163.MCT-11-0115. Epub 2011 Apr 5. Mol Cancer Ther. 2011. PMID: 21467164 Free PMC article.

7

Milatuzumab-SN-38 conjugates for the treatment of CD74+ cancers.

Govindan SV, Cardillo TM, Sharkey RM, Tat F, Gold DV, Goldenberg DM. Govindan SV, et al. Mol Cancer Ther. 2013 Jun;12(6):968-78. doi: 10.1158/1535-7163.MCT-12-1170. Epub 2013 Feb 20. Mol Cancer Ther. 2013. PMID: 23427296

8

Improving the therapeutic index in cancer therapy by using antibody-drug conjugates designed with a moderately cytotoxic drug.

Govindan SV, Cardillo TM, Rossi EA, Trisal P, McBride WJ, Sharkey RM, Goldenberg DM. Govindan SV, et al. Mol Pharm. 2015 Jun 1;12(6):1836-47. doi: 10.1021/mp5006195. Epub 2014 Nov 25. Mol Pharm. 2015. PMID: 25402018 Clinical Trial.

9

Sacituzumab Govitecan (IMMU-132), an Anti-Trop-2/SN-38 Antibody-Drug Conjugate: Characterization and Efficacy in Pancreatic, Gastric, and Other Cancers.

Cardillo TM, Govindan SV, Sharkey RM, Trisal P, Arrojo R, Liu D, Rossi EA, Chang CH, Goldenberg DM. Cardillo TM, et al. Among authors: govindan sv. Bioconjug Chem. 2015 May 20;26(5):919-31. doi: 10.1021/acs.bioconjchem.5b00223. Epub 2015 May 8. Bioconjug Chem. 2015. PMID: 25915780

10

First-in-Human Trial of a Novel Anti-Trop-2 Antibody-SN-38 Conjugate, Sacituzumab Govitecan, for the Treatment of Diverse Metastatic Solid Tumors.

Starodub AN, Ocean AJ, Shah MA, Guarino MJ, Picozzi VJ Jr, Vahdat LT, Thomas SS, Govindan SV, Maliakal PP, Wegener WA, Hamburger SA, Sharkey RM, Goldenberg DM. Starodub AN, et al. Among authors: govindan sv. Clin Cancer Res. 2015 Sep 1;21(17):3870-8. doi: 10.1158/1078-0432.CCR-14-3321. Epub 2015 May 5. Clin Cancer Res. 2015. PMID: 25944802 Free PMC article. Clinical Trial.

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