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Diaryl dihydropyrazole-3-carboxamides with significant in vivo antiobesity activity related to CB1 receptor antagonism: synthesis, biological evaluation, and molecular modeling in the homology model.
Srivastava BK, Joharapurkar A, Raval S, Patel JZ, Soni R, Raval P, Gite A, Goswami A, Sadhwani N, Gandhi N, Patel H, Mishra B, Solanki M, Pandey B, Jain MR, Patel PR. Srivastava BK, et al. Among authors: jain mr. J Med Chem. 2007 Nov 29;50(24):5951-66. doi: 10.1021/jm061490u. Epub 2007 Nov 3. J Med Chem. 2007. PMID: 17979261
Hair growth stimulator property of thienyl substituted pyrazole carboxamide derivatives as a CB1 receptor antagonist with in vivo antiobesity effect.
Srivastava BK, Soni R, Patel JZ, Joharapurkar A, Sadhwani N, Kshirsagar S, Mishra B, Takale V, Gupta S, Pandya P, Kapadnis P, Solanki M, Patel H, Mitra P, Jain MR, Patel PR. Srivastava BK, et al. Among authors: jain mr. Bioorg Med Chem Lett. 2009 May 1;19(9):2546-50. doi: 10.1016/j.bmcl.2009.03.046. Epub 2009 Mar 17. Bioorg Med Chem Lett. 2009. PMID: 19328683
Discovery of orally active, potent, and selective benzotriazole-based PTP1B inhibitors.
Patel D, Jain M, Shah SR, Bahekar R, Jadav P, Darji B, Siriki Y, Bandyopadhyay D, Joharapurkar A, Kshirsagar S, Patel H, Shaikh M, Sairam KV, Patel P. Patel D, et al. Among authors: jain m. ChemMedChem. 2011 Jun 6;6(6):1011-6. doi: 10.1002/cmdc.201100077. Epub 2011 Apr 19. ChemMedChem. 2011. PMID: 21506278 No abstract available.
Long-acting peptidomimetics based DPP-IV inhibitors.
Jadav P, Bahekar R, Shah SR, Patel D, Joharapurkar A, Kshirsagar S, Jain M, Shaikh M, Sairam KV. Jadav P, et al. Among authors: jain m. Bioorg Med Chem Lett. 2012 May 15;22(10):3516-21. doi: 10.1016/j.bmcl.2012.03.078. Epub 2012 Mar 28. Bioorg Med Chem Lett. 2012. PMID: 22503246
4,356 results