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Development of Selective Pyrido[2,3-d]pyrimidin-7(8H)-one-Based Mammalian STE20-Like (MST3/4) Kinase Inhibitors.
Rak M, Menge A, Tesch R, Berger LM, Balourdas DI, Shevchenko E, Krämer A, Elson L, Berger BT, Abdi I, Wahl LM, Poso A, Kaiser A, Hanke T, Kronenberger T, Joerger AC, Müller S, Knapp S. Rak M, et al. Among authors: poso a. J Med Chem. 2024 Mar 14;67(5):3813-3842. doi: 10.1021/acs.jmedchem.3c02217. Epub 2024 Feb 29. J Med Chem. 2024. PMID: 38422480
Structure-based design of pseudopeptidic inhibitors for SIRT1 and SIRT2.
Huhtiniemi T, Salo HS, Suuronen T, Poso A, Salminen A, Leppänen J, Jarho E, Lahtela-Kakkonen M. Huhtiniemi T, et al. Among authors: poso a. J Med Chem. 2011 Oct 13;54(19):6456-68. doi: 10.1021/jm200590k. Epub 2011 Sep 7. J Med Chem. 2011. PMID: 21895016
Chiral 1,3,4-oxadiazol-2-ones as highly selective FAAH inhibitors.
Patel JZ, Parkkari T, Laitinen T, Kaczor AA, Saario SM, Savinainen JR, Navia-Paldanius D, Cipriano M, Leppänen J, Koshevoy IO, Poso A, Fowler CJ, Laitinen JT, Nevalainen T. Patel JZ, et al. Among authors: poso a. J Med Chem. 2013 Nov 14;56(21):8484-96. doi: 10.1021/jm400923s. Epub 2013 Oct 22. J Med Chem. 2013. PMID: 24083878
Peptides and Pseudopeptides as SIRT6 Deacetylation Inhibitors.
Kokkonen P, Rahnasto-Rilla M, Kiviranta PH, Huhtiniemi T, Laitinen T, Poso A, Jarho E, Lahtela-Kakkonen M. Kokkonen P, et al. Among authors: poso a. ACS Med Chem Lett. 2012 Oct 23;3(12):969-74. doi: 10.1021/ml300139n. eCollection 2012 Dec 13. ACS Med Chem Lett. 2012. PMID: 24900419 Free PMC article.
Acylated 1H-1,2,4-Triazol-5-amines Targeting Human Coagulation Factor XIIa and Thrombin: Conventional and Microscale Synthesis, Anticoagulant Properties, and Mechanism of Action.
Korff M, Imberg L, Will JM, Bückreiß N, Kalinina SA, Wenzel BM, Kastner GA, Daniliuc CG, Barth M, Ovsepyan RA, Butov KR, Humpf HU, Lehr M, Panteleev MA, Poso A, Karst U, Steinmetzer T, Bendas G, Kalinin DV. Korff M, et al. Among authors: poso a. J Med Chem. 2020 Nov 12;63(21):13159-13186. doi: 10.1021/acs.jmedchem.0c01635. Epub 2020 Oct 22. J Med Chem. 2020. PMID: 33089691
297 results