Linton KJ - Search Results

1

Structural basis for the modulation of MRP2 activity by phosphorylation and drugs.

Mazza T, Roumeliotis TI, Garitta E, Drew D, Rashid ST, Indiveri C, Choudhary JS, Linton KJ, Beis K. Mazza T, et al. Among authors: linton kj. Nat Commun. 2024 Mar 4;15(1):1983. doi: 10.1038/s41467-024-46392-8. Nat Commun. 2024. PMID: 38438394 Free PMC article.

2

Membrane phosphatidylserine distribution as a non-apoptotic signalling mechanism in lymphocytes.

Elliott JI, Surprenant A, Marelli-Berg FM, Cooper JC, Cassady-Cain RL, Wooding C, Linton K, Alexander DR, Higgins CF. Elliott JI, et al. Nat Cell Biol. 2005 Aug;7(8):808-16. doi: 10.1038/ncb1279. Epub 2005 Jul 17. Nat Cell Biol. 2005. PMID: 16025105

3

Molecular Modeling Studies to Probe the Binding Hypothesis of Novel Lead Compounds against Multidrug Resistance Protein ABCB1.

Cheema Y, Linton KJ, Jabeen I. Cheema Y, et al. Among authors: linton kj. Biomolecules. 2024 Jan 16;14(1):114. doi: 10.3390/biom14010114. Biomolecules. 2024. PMID: 38254714 Free PMC article.

4

ABCB1 Does Not Require the Side-Chain Hydrogen-Bond Donors Gln³⁴⁷, Gln⁷²⁵, Gln⁹⁹⁰ to Confer Cellular Resistance to the Anticancer Drug Taxol.

Sasitharan K, Iqbal HA, Bifsa F, Olszewska A, Linton KJ. Sasitharan K, et al. Among authors: linton kj. Int J Mol Sci. 2021 Aug 9;22(16):8561. doi: 10.3390/ijms22168561. Int J Mol Sci. 2021. PMID: 34445264 Free PMC article.

5

The ATP switch model for ABC transporters.

Higgins CF, Linton KJ. Higgins CF, et al. Among authors: linton kj. Nat Struct Mol Biol. 2004 Oct;11(10):918-26. doi: 10.1038/nsmb836. Nat Struct Mol Biol. 2004. PMID: 15452563 Review.

6

Identification and Empiric Evaluation of New Inhibitors of the Multidrug Transporter P-Glycoprotein (ABCB1).

Cheema Y, Kiani YS, Linton KJ, Jabeen I. Cheema Y, et al. Among authors: linton kj. Int J Mol Sci. 2023 Mar 10;24(6):5298. doi: 10.3390/ijms24065298. Int J Mol Sci. 2023. PMID: 36982374 Free PMC article.

7

Canalicular ABC transporters and liver disease.

Nicolaou M, Andress EJ, Zolnerciks JK, Dixon PH, Williamson C, Linton KJ. Nicolaou M, et al. Among authors: linton kj. J Pathol. 2012 Jan;226(2):300-15. doi: 10.1002/path.3019. J Pathol. 2012. PMID: 21984474 Review.

8

The multidrug resistance pump ABCB1 is a substrate for the ubiquitin ligase NEDD4-1.

Akkaya BG, Zolnerciks JK, Ritchie TK, Bauer B, Hartz AM, Sullivan JA, Linton KJ. Akkaya BG, et al. Among authors: linton kj. Mol Membr Biol. 2015;32(2):39-45. doi: 10.3109/09687688.2015.1023378. Epub 2015 May 26. Mol Membr Biol. 2015. PMID: 26006083 Free PMC article.

9

Structure of ABC transporters.

Zolnerciks JK, Andress EJ, Nicolaou M, Linton KJ. Zolnerciks JK, et al. Among authors: linton kj. Essays Biochem. 2011 Sep 7;50(1):43-61. doi: 10.1042/bse0500043. Essays Biochem. 2011. PMID: 21967051 Review.

10

The Q loops of the human multidrug resistance transporter ABCB1 are necessary to couple drug binding to the ATP catalytic cycle.

Zolnerciks JK, Akkaya BG, Snippe M, Chiba P, Seelig A, Linton KJ. Zolnerciks JK, et al. Among authors: linton kj. FASEB J. 2014 Oct;28(10):4335-46. doi: 10.1096/fj.13-245639. Epub 2014 Jul 11. FASEB J. 2014. PMID: 25016028

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