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Single-cell guided prenatal derivation of primary fetal epithelial organoids from human amniotic and tracheal fluids.
Gerli MFM, Calà G, Beesley MA, Sina B, Tullie L, Sun KY, Panariello F, Michielin F, Davidson JR, Russo FM, Jones BC, Lee DDH, Savvidis S, Xenakis T, Simcock IC, Straatman-Iwanowska AA, Hirst RA, David AL, O'Callaghan C, Olivo A, Eaton S, Loukogeorgakis SP, Cacchiarelli D, Deprest J, Li VSW, Giobbe GG, De Coppi P. Gerli MFM, et al. Among authors: hirst ra. Nat Med. 2024 Mar;30(3):875-887. doi: 10.1038/s41591-024-02807-z. Epub 2024 Mar 4. Nat Med. 2024. PMID: 38438734 Free PMC article.
Axonemal structures reveal mechanoregulatory and disease mechanisms.
Walton T, Gui M, Velkova S, Fassad MR, Hirst RA, Haarman E, O'Callaghan C, Bottier M, Burgoyne T, Mitchison HM, Brown A. Walton T, et al. Among authors: hirst ra. Nature. 2023 Jun;618(7965):625-633. doi: 10.1038/s41586-023-06140-2. Epub 2023 May 31. Nature. 2023. PMID: 37258679 Free PMC article.
Mutations in axonemal dynein assembly factor DNAAF3 cause primary ciliary dyskinesia.
Mitchison HM, Schmidts M, Loges NT, Freshour J, Dritsoula A, Hirst RA, O'Callaghan C, Blau H, Al Dabbagh M, Olbrich H, Beales PL, Yagi T, Mussaffi H, Chung EM, Omran H, Mitchell DR. Mitchison HM, et al. Among authors: hirst ra. Nat Genet. 2012 Mar 4;44(4):381-9, S1-2. doi: 10.1038/ng.1106. Nat Genet. 2012. PMID: 22387996 Free PMC article.
Severe asthma: Differential chemokine response of airway epithelial cells.
Thomas B, Hirst RA, Brett-Pitt MH, Williams G, Andrew PW, Sousa AR, Marshall RP, Brightling C, O'Callaghan C. Thomas B, et al. Among authors: hirst ra. J Allergy Clin Immunol. 2017 Oct;140(4):1149-1152.e10. doi: 10.1016/j.jaci.2017.02.040. Epub 2017 Apr 12. J Allergy Clin Immunol. 2017. PMID: 28412395 No abstract available.
89 results