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Lack of p38 activation in T cells increases IL-35 and protects against obesity by promoting thermogenesis.
Nikolic I, Ruiz-Garrido I, Crespo M, Romero-Becerra R, Leiva-Vega L, Mora A, León M, Rodríguez E, Leiva M, Plata-Gómez AB, Alvarez Flores MB, Torres JL, Hernández-Cosido L, López JA, Vázquez J, Efeyan A, Martin P, Marcos M, Sabio G. Nikolic I, et al. Among authors: efeyan a. EMBO Rep. 2024 May 10. doi: 10.1038/s44319-024-00149-y. Online ahead of print. EMBO Rep. 2024. PMID: 38730210 Free article.
Sexual dimorphism in the antitumor immune responses elicited by the combination of fasting and chemotherapy.
Pastor-Fernández A, Gómez de Las Heras MM, Escrig-Larena JI, Barradas M, Pantoja C, Plaza A, Lopez-Aceituno JL, Durán E, Efeyan A, Mittelbrunn M, Martinez L, Fernandez-Marcos PJ. Pastor-Fernández A, et al. Among authors: efeyan a. Cancer Commun (Lond). 2024 Apr;44(4):508-513. doi: 10.1002/cac2.12535. Epub 2024 Mar 21. Cancer Commun (Lond). 2024. PMID: 38512765 Free PMC article. No abstract available.
Hepatic nutrient and hormone signaling to mTORC1 instructs the postnatal metabolic zonation of the liver.
Plata-Gómez AB, de Prado-Rivas L, Sanz A, Deleyto-Seldas N, García F, de la Calle Arregui C, Silva C, Caleiras E, Graña-Castro O, Piñeiro-Yáñez E, Krebs J, Leiva-Vega L, Muñoz J, Jain A, Sabio G, Efeyan A. Plata-Gómez AB, et al. Among authors: efeyan a. Nat Commun. 2024 Mar 18;15(1):1878. doi: 10.1038/s41467-024-46032-1. Nat Commun. 2024. PMID: 38499523 Free PMC article.
NGFR regulates stromal cell activation in germinal centers.
Hernández-Barranco A, Santos V, Mazariegos MS, Caleiras E, Nogués L, Mourcin F, Léonard S, Oblet C, Genebrier S, Rossille D, Benguría A, Sanz A, Vázquez E, Dopazo A, Efeyan A, Ortega-Molina A, Cogne M, Tarte K, Peinado H. Hernández-Barranco A, et al. Among authors: efeyan a. Cell Rep. 2024 Feb 27;43(2):113705. doi: 10.1016/j.celrep.2024.113705. Epub 2024 Feb 1. Cell Rep. 2024. PMID: 38307025 Free article.
Pharmacological and genetic increases in liver NADPH levels ameliorate NASH progression in female mice.
Rodriguez-Ramiro I, Pastor-Fernández A, López-Aceituno JL, Garcia-Dominguez E, Sierra-Ramirez A, Valverde AM, Martinez-Pastor B, Efeyan A, Gomez-Cabrera MC, Viña J, Fernandez-Marcos PJ. Rodriguez-Ramiro I, et al. Among authors: efeyan a. Free Radic Biol Med. 2024 Jan;210:448-461. doi: 10.1016/j.freeradbiomed.2023.11.019. Epub 2023 Nov 29. Free Radic Biol Med. 2024. PMID: 38036067 Free article.
PI3K-C2β limits mTORC1 signaling and angiogenic growth.
Kobialka P, Llena J, Deleyto-Seldas N, Munar-Gelabert M, Dengra JA, Villacampa P, Albinyà-Pedrós A, Muixi L, Andrade J, van Splunder H, Angulo-Urarte A, Potente M, Grego-Bessa J, Castillo SD, Vanhaesebroeck B, Efeyan A, Graupera M. Kobialka P, et al. Among authors: efeyan a. Sci Signal. 2023 Nov 28;16(813):eadg1913. doi: 10.1126/scisignal.adg1913. Epub 2023 Nov 28. Sci Signal. 2023. PMID: 38015911
AMPK knocks at the gate of GATOR.
Deleyto-Seldas N, Efeyan A. Deleyto-Seldas N, et al. Among authors: efeyan a. Nat Metab. 2023 Feb;5(2):197-198. doi: 10.1038/s42255-022-00729-z. Nat Metab. 2023. PMID: 36732623 No abstract available.
Folliculin-interacting protein FNIP2 impacts on overweight and obesity through a polymorphism in a conserved 3' untranslated region.
Fernández LP, Deleyto-Seldas N, Colmenarejo G, Sanz A, Wagner S, Plata-Gómez AB, Gómez-Patiño M, Molina S, Espinosa-Salinas I, Aguilar-Aguilar E, Ortega S, Graña-Castro O, Loria-Kohen V, Fernández-Marcos PJ, Efeyan A, Ramírez de Molina A. Fernández LP, et al. Among authors: efeyan a. Genome Biol. 2022 Oct 31;23(1):230. doi: 10.1186/s13059-022-02798-5. Genome Biol. 2022. PMID: 36316722 Free PMC article.
54 results