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A longitudinal MRI and TSPO PET-based investigation of brain region-specific neuroprotection by diazepam versus midazolam following organophosphate-induced seizures.
Hobson BA, Rowland DJ, Dou Y, Saito N, Harmany ZT, Bruun DA, Harvey DJ, Chaudhari AJ, Garbow JR, Lein PJ. Hobson BA, et al. Among authors: saito n. Neuropharmacology. 2024 Jun 15;251:109918. doi: 10.1016/j.neuropharm.2024.109918. Epub 2024 Mar 24. Neuropharmacology. 2024. PMID: 38527652 Free article.
The chemical convulsant diisopropylfluorophosphate (DFP) causes persistent neuropathology in adult male rats independent of seizure activity.
González EA, Rindy AC, Guignet MA, Calsbeek JJ, Bruun DA, Dhir A, Andrew P, Saito N, Rowland DJ, Harvey DJ, Rogawski MA, Lein PJ. González EA, et al. Among authors: saito n. Arch Toxicol. 2020 Jun;94(6):2149-2162. doi: 10.1007/s00204-020-02747-w. Epub 2020 Apr 18. Arch Toxicol. 2020. PMID: 32303805 Free PMC article.
Acute administration of diazepam or midazolam minimally alters long-term neuropathological effects in the rat brain following acute intoxication with diisopropylfluorophosphate.
Supasai S, González EA, Rowland DJ, Hobson B, Bruun DA, Guignet MA, Soares S, Singh V, Wulff H, Saito N, Harvey DJ, Lein PJ. Supasai S, et al. Among authors: saito n. Eur J Pharmacol. 2020 Nov 5;886:173538. doi: 10.1016/j.ejphar.2020.173538. Epub 2020 Sep 6. Eur J Pharmacol. 2020. PMID: 32898549 Free PMC article.
Persistent neuropathology and behavioral deficits in a mouse model of status epilepticus induced by acute intoxication with diisopropylfluorophosphate.
Calsbeek JJ, González EA, Bruun DA, Guignet MA, Copping N, Dawson ME, Yu AJ, MacMahon JA, Saito NH, Harvey DJ, Silverman JL, Lein PJ. Calsbeek JJ, et al. Among authors: saito nh. Neurotoxicology. 2021 Dec;87:106-119. doi: 10.1016/j.neuro.2021.09.001. Epub 2021 Sep 9. Neurotoxicology. 2021. PMID: 34509511 Free PMC article.
3,422 results