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Breast cancer dependence on MCL-1 is due to its canonical anti-apoptotic function.
Campbell KJ, Mason SM, Winder ML, Willemsen RBE, Cloix C, Lawson H, Rooney N, Dhayade S, Sims AH, Blyth K, Tait SWG. Campbell KJ, et al. Among authors: tait swg. Cell Death Differ. 2021 Sep;28(9):2589-2600. doi: 10.1038/s41418-021-00773-4. Epub 2021 Mar 31. Cell Death Differ. 2021. PMID: 33785871 Free PMC article.
Targeting BCL-2 regulated apoptosis in cancer.
Campbell KJ, Tait SWG. Campbell KJ, et al. Among authors: tait swg. Open Biol. 2018 May;8(5):180002. doi: 10.1098/rsob.180002. Open Biol. 2018. PMID: 29769323 Free PMC article. Review.
Mitochondrial DNA in cell death and inflammation.
Heilig R, Lee J, Tait SWG. Heilig R, et al. Among authors: tait swg. Biochem Soc Trans. 2023 Feb 27;51(1):457-472. doi: 10.1042/BST20221525. Biochem Soc Trans. 2023. PMID: 36815695 Free PMC article. Review.
Mitochondria as multifaceted regulators of cell death.
Bock FJ, Tait SWG. Bock FJ, et al. Among authors: tait swg. Nat Rev Mol Cell Biol. 2020 Feb;21(2):85-100. doi: 10.1038/s41580-019-0173-8. Epub 2019 Oct 21. Nat Rev Mol Cell Biol. 2020. PMID: 31636403 Free article. Review.
Venetoclax causes metabolic reprogramming independent of BCL-2 inhibition.
Roca-Portoles A, Rodriguez-Blanco G, Sumpton D, Cloix C, Mullin M, Mackay GM, O'Neill K, Lemgruber L, Luo X, Tait SWG. Roca-Portoles A, et al. Among authors: tait swg. Cell Death Dis. 2020 Aug 13;11(8):616. doi: 10.1038/s41419-020-02867-2. Cell Death Dis. 2020. PMID: 32792521 Free PMC article.
Increased apoptotic sensitivity of glioblastoma enables therapeutic targeting by BH3-mimetics.
Koessinger AL, Cloix C, Koessinger D, Heiland DH, Bock FJ, Strathdee K, Kinch K, Martínez-Escardó L, Paul NR, Nixon C, Malviya G, Jackson MR, Campbell KJ, Stevenson K, Davis S, Elmasry Y, Ahmed A, O'Prey J, Ichim G, Schnell O, Stewart W, Blyth K, Ryan KM, Chalmers AJ, Norman JC, Tait SWG. Koessinger AL, et al. Among authors: tait swg. Cell Death Differ. 2022 Oct;29(10):2089-2104. doi: 10.1038/s41418-022-01001-3. Epub 2022 Apr 26. Cell Death Differ. 2022. PMID: 35473984 Free PMC article.
99 results