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Podoplanin maintains high endothelial venule integrity by interacting with platelet CLEC-2.
Herzog BH, Fu J, Wilson SJ, Hess PR, Sen A, McDaniel JM, Pan Y, Sheng M, Yago T, Silasi-Mansat R, McGee S, May F, Nieswandt B, Morris AJ, Lupu F, Coughlin SR, McEver RP, Chen H, Kahn ML, Xia L. Herzog BH, et al. Among authors: fu j. Nature. 2013 Oct 3;502(7469):105-9. doi: 10.1038/nature12501. Epub 2013 Sep 1. Nature. 2013. PMID: 23995678 Free PMC article.
Loss of Core 1-derived O-Glycans Decreases Breast Cancer Development in Mice.
Song K, Herzog BH, Fu J, Sheng M, Bergstrom K, McDaniel JM, Kondo Y, McGee S, Cai X, Li P, Chen H, Xia L. Song K, et al. Among authors: fu j. J Biol Chem. 2015 Aug 14;290(33):20159-66. doi: 10.1074/jbc.M115.654483. Epub 2015 Jun 29. J Biol Chem. 2015. PMID: 26124270 Free PMC article.
CLEC-2 and podoplanin, partners again.
Fu J, Xia L. Fu J, et al. Blood. 2016 Mar 31;127(13):1629-30. doi: 10.1182/blood-2016-02-695445. Blood. 2016. PMID: 27034419 Free PMC article.
The CLEC-2-podoplanin axis controls the contractility of fibroblastic reticular cells and lymph node microarchitecture.
Astarita JL, Cremasco V, Fu J, Darnell MC, Peck JR, Nieves-Bonilla JM, Song K, Kondo Y, Woodruff MC, Gogineni A, Onder L, Ludewig B, Weimer RM, Carroll MC, Mooney DJ, Xia L, Turley SJ. Astarita JL, et al. Among authors: fu j. Nat Immunol. 2015 Jan;16(1):75-84. doi: 10.1038/ni.3035. Epub 2014 Oct 27. Nat Immunol. 2015. PMID: 25347465 Free PMC article.
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