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TGF-β inhibition combined with cytotoxic nanomedicine normalizes triple negative breast cancer microenvironment towards anti-tumor immunity.
Panagi M, Voutouri C, Mpekris F, Papageorgis P, Martin MR, Martin JD, Demetriou P, Pierides C, Polydorou C, Stylianou A, Louca M, Koumas L, Costeas P, Kataoka K, Cabral H, Stylianopoulos T. Panagi M, et al. Among authors: martin jd, martin mr. Theranostics. 2020 Jan 12;10(4):1910-1922. doi: 10.7150/thno.36936. eCollection 2020. Theranostics. 2020. PMID: 32042344 Free PMC article.
Polymeric micelles effectively reprogram the tumor microenvironment to potentiate nano-immunotherapy in mouse breast cancer models.
Panagi M, Mpekris F, Chen P, Voutouri C, Nakagawa Y, Martin JD, Hiroi T, Hashimoto H, Demetriou P, Pierides C, Samuel R, Stylianou A, Michael C, Fukushima S, Georgiou P, Papageorgis P, Papaphilippou PC, Koumas L, Costeas P, Ishii G, Kojima M, Kataoka K, Cabral H, Stylianopoulos T. Panagi M, et al. Among authors: martin jd. Nat Commun. 2022 Nov 22;13(1):7165. doi: 10.1038/s41467-022-34744-1. Nat Commun. 2022. PMID: 36418896 Free PMC article.
Dexamethasone Increases Cisplatin-Loaded Nanocarrier Delivery and Efficacy in Metastatic Breast Cancer by Normalizing the Tumor Microenvironment.
Martin JD, Panagi M, Wang C, Khan TT, Martin MR, Voutouri C, Toh K, Papageorgis P, Mpekris F, Polydorou C, Ishii G, Takahashi S, Gotohda N, Suzuki T, Wilhelm ME, Melo VA, Quader S, Norimatsu J, Lanning RM, Kojima M, Stuber MD, Stylianopoulos T, Kataoka K, Cabral H. Martin JD, et al. Among authors: martin mr. ACS Nano. 2019 Jun 25;13(6):6396-6408. doi: 10.1021/acsnano.8b07865. Epub 2019 Jun 12. ACS Nano. 2019. PMID: 31187975
Normalizing the Microenvironment Overcomes Vessel Compression and Resistance to Nano-immunotherapy in Breast Cancer Lung Metastasis.
Mpekris F, Panagi M, Voutouri C, Martin JD, Samuel R, Takahashi S, Gotohda N, Suzuki T, Papageorgis P, Demetriou P, Pierides C, Koumas L, Costeas P, Kojima M, Ishii G, Constantinidou A, Kataoka K, Cabral H, Stylianopoulos T. Mpekris F, et al. Among authors: martin jd. Adv Sci (Weinh). 2020 Dec 13;8(3):2001917. doi: 10.1002/advs.202001917. eCollection 2021 Feb. Adv Sci (Weinh). 2020. PMID: 33552852 Free PMC article.
Remodeling tumor microenvironment with nanomedicines.
Martin JD, Miyazaki T, Cabral H. Martin JD, et al. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2021 Nov;13(6):e1730. doi: 10.1002/wnan.1730. Epub 2021 Jun 14. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2021. PMID: 34124849 Review.
Multiphoton Phosphorescence Quenching Microscopy Reveals Kinetics of Tumor Oxygenation during Antiangiogenesis and Angiotensin Signaling Inhibition.
Martin JD, Lanning RM, Chauhan VP, Martin MR, Mousa AS, Kamoun WS, Han HS, Lee H, Stylianopoulos T, Bawendi MG, Duda DG, Brown EB, Padera TP, Fukumura D, Jain RK. Martin JD, et al. Among authors: martin mr. Clin Cancer Res. 2022 Jul 15;28(14):3076-3090. doi: 10.1158/1078-0432.CCR-22-0486. Clin Cancer Res. 2022. PMID: 35584239 Free PMC article.
451 results