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The Pan-RAF-MEK Nondegrading Molecular Glue NST-628 Is a Potent and Brain-Penetrant Inhibitor of the RAS-MAPK Pathway with Activity across Diverse RAS- and RAF-Driven Cancers.
Cancer Discov. 2024 Jul 1;14(7):1190-1205. doi: 10.1158/2159-8290.CD-24-0139.
Cancer Discov. 2024.
PMID: 38588399
Free PMC article.
Monitoring GAPDH activity and inhibition with cysteine-reactive chemical probes.
Canarelli SE, Swalm BM, Larson ET, Morrison MJ, Weerapana E.
Canarelli SE, et al. Among authors: swalm bm.
RSC Chem Biol. 2022 Jun 9;3(7):972-982. doi: 10.1039/d2cb00091a. eCollection 2022 Jul 6.
RSC Chem Biol. 2022.
PMID: 35866162
Free PMC article.
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The Discovery of Two Novel Classes of 5,5-Bicyclic Nucleoside-Derived PRMT5 Inhibitors for the Treatment of Cancer.
Quiroz RV, Reutershan MH, Schneider SE, Sloman D, Lacey BM, Swalm BM, Yeung CS, Gibeau C, Spellman DS, Rankic DA, Chen D, Witter D, Linn D, Munsell E, Feng G, Xu H, Hughes JME, Lim J, Saurí J, Geddes K, Wan M, Mansueto MS, Follmer NE, Fier PS, Siliphaivanh P, Daublain P, Palte RL, Hayes RP, Lee S, Kawamura S, Silverman S, Sanyal S, Henderson TJ, Ye Y, Gao Y, Nicholson B, Machacek MR.
Quiroz RV, et al. Among authors: swalm bm.
J Med Chem. 2021 Apr 8;64(7):3911-3939. doi: 10.1021/acs.jmedchem.0c02083. Epub 2021 Mar 23.
J Med Chem. 2021.
PMID: 33755451
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Reaction coupling between wild-type and disease-associated mutant EZH2.
Swalm BM, Knutson SK, Warholic NM, Jin L, Kuntz KW, Keilhack H, Smith JJ, Pollock RM, Moyer MP, Scott MP, Copeland RA, Wigle TJ.
Swalm BM, et al.
ACS Chem Biol. 2014 Nov 21;9(11):2459-64. doi: 10.1021/cb500548b. Epub 2014 Aug 28.
ACS Chem Biol. 2014.
PMID: 25154026
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Convergent evolution of chromatin modification by structurally distinct enzymes: comparative enzymology of histone H3 Lys²⁷ methylation by human polycomb repressive complex 2 and vSET.
Swalm BM, Hallenbeck KK, Majer CR, Jin L, Scott MP, Moyer MP, Copeland RA, Wigle TJ.
Swalm BM, et al.
Biochem J. 2013 Jul 15;453(2):241-7. doi: 10.1042/BJ20130439.
Biochem J. 2013.
PMID: 23679895
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