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ATF3 and CH25H regulate effector trogocytosis and anti-tumor activities of endogenous and immunotherapeutic cytotoxic T lymphocytes.
Lu Z, McBrearty N, Chen J, Tomar VS, Zhang H, De Rosa G, Tan A, Weljie AM, Beiting DP, Miao Z, George SS, Berger A, Saggu G, Diehl JA, Koumenis C, Fuchs SY. Lu Z, et al. Among authors: mcbrearty n. Cell Metab. 2024 May 7;36(5):1164-1167. doi: 10.1016/j.cmet.2024.04.002. Epub 2024 Apr 11. Cell Metab. 2024. PMID: 38604169 No abstract available.
Tumor-Suppressive and Immune-Stimulating Roles of Cholesterol 25-hydroxylase in Pancreatic Cancer Cells.
McBrearty N, Cho C, Chen J, Zahedi F, Peck AR, Radaelli E, Assenmacher CA, Pavlak C, Devine A, Yu P, Lu Z, Zhang H, Li J, Pitarresi JR, Astsaturov I, Cukierman E, Rustgi AK, Stanger BZ, Rui H, Fuchs SY. McBrearty N, et al. Mol Cancer Res. 2023 Mar 1;21(3):228-239. doi: 10.1158/1541-7786.MCR-22-0602. Mol Cancer Res. 2023. PMID: 36378658 Free PMC article.
Protection of Regulatory T Cells from Fragility and Inactivation in the Tumor Microenvironment.
Zhang H, Tomar VS, Li J, Basavaraja R, Yan F, Gui J, McBrearty N, Costich TL, Beiting DP, Blanco MA, Conejo-Garcia JR, Saggu G, Berger A, Nefedova Y, Gabrilovich DI, Fuchs SY. Zhang H, et al. Among authors: mcbrearty n. Cancer Immunol Res. 2022 Dec 2;10(12):1490-1505. doi: 10.1158/2326-6066.CIR-22-0295. Cancer Immunol Res. 2022. PMID: 36255418 Free PMC article.
ATF3 and CH25H regulate effector trogocytosis and anti-tumor activities of endogenous and immunotherapeutic cytotoxic T lymphocytes.
Lu Z, McBrearty N, Chen J, Tomar VS, Zhang H, De Rosa G, Tan A, Weljie AM, Beiting DP, Miao Z, George SS, Berger A, Saggu G, Diehl JA, Koumenis C, Fuchs SY. Lu Z, et al. Among authors: mcbrearty n. Cell Metab. 2022 Sep 6;34(9):1342-1358.e7. doi: 10.1016/j.cmet.2022.08.007. Cell Metab. 2022. PMID: 36070682 Free PMC article.
Induction of the activating transcription factor-4 in the intratumoral CD8+ T cells sustains their viability and anti-tumor activities.
Lu Z, Bae EA, Verginadis II, Zhang H, Cho C, McBrearty N, George SS, Diehl JA, Koumenis C, Bradley LM, Fuchs SY. Lu Z, et al. Among authors: mcbrearty n. Cancer Immunol Immunother. 2023 Apr;72(4):815-826. doi: 10.1007/s00262-022-03286-2. Epub 2022 Sep 5. Cancer Immunol Immunother. 2023. PMID: 36063172 Free PMC article.