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Immunoglobulin replacement products protect against SARS-CoV-2 infection in vivo despite poor neutralizing activity.
Zimmerman O, Altman Doss AM, Ying B, Liang CY, Mackin SR, Davis-Adams HG, Adams LJ, VanBlargan LA, Chen RE, Scheaffer SM, Desai P, Raju S, Mantia TL, O'Shaughnessy CC, Monroy JM, Wedner HJ, Rigell CJ, Kau AL, Dy TB, Ren Z, Turner JS, O'Halloran JA, Presti RM, Kendall PL, Fremont DH, Ellebedy AH, Diamond MS. Zimmerman O, et al. Among authors: chen re. JCI Insight. 2024 Feb 8;9(3):e176359. doi: 10.1172/jci.insight.176359. JCI Insight. 2024. PMID: 38175703 Free PMC article.
A broadly reactive antibody targeting the N-terminal domain of SARS-CoV-2 spike confers Fc-mediated protection.
Adams LJ, VanBlargan LA, Liu Z, Gilchuk P, Zhao H, Chen RE, Raju S, Chong Z, Whitener BM, Shrihari S, Jethva PN, Gross ML, Crowe JE Jr, Whelan SPJ, Diamond MS, Fremont DH. Adams LJ, et al. Among authors: chen re. Cell Rep Med. 2023 Dec 19;4(12):101305. doi: 10.1016/j.xcrm.2023.101305. Epub 2023 Nov 30. Cell Rep Med. 2023. PMID: 38039973 Free PMC article.
Pemphigoid gestationis treated with dupilumab.
Chen RE, Yokoyama CC, Anadkat MJ. Chen RE, et al. JAAD Case Rep. 2023 Sep 7;41:10-12. doi: 10.1016/j.jdcr.2023.08.013. eCollection 2023 Nov. JAAD Case Rep. 2023. PMID: 37842158 Free PMC article. No abstract available.
prM-reactive antibodies reveal a role for partially mature virions in dengue virus pathogenesis.
Dowd KA, Sirohi D, Speer SD, VanBlargan LA, Chen RE, Mukherjee S, Whitener BM, Govero J, Aleshnick M, Larman B, Sukupolvi-Petty S, Sevvana M, Miller AS, Klose T, Zheng A, Koenig S, Kielian M, Kuhn RJ, Diamond MS, Pierson TC. Dowd KA, et al. Among authors: chen re. Proc Natl Acad Sci U S A. 2023 Jan 17;120(3):e2218899120. doi: 10.1073/pnas.2218899120. Epub 2023 Jan 13. Proc Natl Acad Sci U S A. 2023. PMID: 36638211 Free PMC article.
126 results