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Multi-omic analysis of Esophageal Adenocarcinoma uncovers candidate therapeutic targets and cancer-selective post-transcriptional regulation.
O'Neill JR, Yébenes Mayordomo M, Mitulović G, Al Shboul S, Bedran G, Faktor J, Hernychova L, Uhrik L, Gomez-Herranz M, Kocikowski M, Save V, Vojtěšek B, Arends M; OCCAMS consortium; Hupp T, Alfaro J. O'Neill JR, et al. Among authors: save v. Mol Cell Proteomics. 2024 Apr 9:100764. doi: 10.1016/j.mcpro.2024.100764. Online ahead of print. Mol Cell Proteomics. 2024. PMID: 38604503 Free article.
Mutational signatures in esophageal adenocarcinoma define etiologically distinct subgroups with therapeutic relevance.
Secrier M, Li X, de Silva N, Eldridge MD, Contino G, Bornschein J, MacRae S, Grehan N, O'Donovan M, Miremadi A, Yang TP, Bower L, Chettouh H, Crawte J, Galeano-Dalmau N, Grabowska A, Saunders J, Underwood T, Waddell N, Barbour AP, Nutzinger B, Achilleos A, Edwards PA, Lynch AG, Tavaré S, Fitzgerald RC; Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) Consortium. Secrier M, et al. Nat Genet. 2016 Oct;48(10):1131-41. doi: 10.1038/ng.3659. Epub 2016 Sep 5. Nat Genet. 2016. PMID: 27595477 Free PMC article.
Authentication and characterisation of a new oesophageal adenocarcinoma cell line: MFD-1.
Garcia E, Hayden A, Birts C, Britton E, Cowie A, Pickard K, Mellone M, Choh C, Derouet M, Duriez P, Noble F, White MJ, Primrose JN, Strefford JC, Rose-Zerilli M, Thomas GJ, Ang Y, Sharrocks AD, Fitzgerald RC, Underwood TJ; OCCAMS consortium. Garcia E, et al. Sci Rep. 2016 Sep 7;6:32417. doi: 10.1038/srep32417. Sci Rep. 2016. PMID: 27600491 Free PMC article.
A comparative analysis of whole genome sequencing of esophageal adenocarcinoma pre- and post-chemotherapy.
Noorani A, Bornschein J, Lynch AG, Secrier M, Achilleos A, Eldridge M, Bower L, Weaver JMJ, Crawte J, Ong CA, Shannon N, MacRae S, Grehan N, Nutzinger B, O'Donovan M, Hardwick R, Tavaré S, Fitzgerald RC; Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) Consortium. Noorani A, et al. Genome Res. 2017 Jun;27(6):902-912. doi: 10.1101/gr.214296.116. Epub 2017 May 2. Genome Res. 2017. PMID: 28465312 Free PMC article.
Patients unfit for neoadjuvant therapy may still undergo resection of locally advanced esophageal or esophagogastric junctional cancer with acceptable oncological results.
O'Neill JR, Kennedy ED, Save V, Langdale-Brown B, Wall L, Skipworth RJE, Paterson-Brown S. O'Neill JR, et al. Among authors: save v. Int J Surg Oncol (N Y). 2017 Feb;2(2):e09. doi: 10.1097/IJ9.0000000000000009. Epub 2017 Jan 13. Int J Surg Oncol (N Y). 2017. PMID: 29177210 Free PMC article.
Author Correction: Authentication and characterisation of a new oesophageal adenocarcinoma cell line: MFD-1.
Garcia E, Hayden A, Birts C, Britton E, Rogerson C, Bleaney CW, Cowie A, Pickard K, Mellone M, Choh C, Derouet M, Duriez P, Noble F, White MJ, Primrose JN, Strefford JC, Rose-Zerilli M, Thomas GJ, Ang Y, Sharrocks AD, Fitzgerald RC, Underwood TJ; OCCAMS consortium. Garcia E, et al. Sci Rep. 2019 Jan 22;9(1):318. doi: 10.1038/s41598-018-37591-7. Sci Rep. 2019. PMID: 30670740 Free PMC article.
The landscape of selection in 551 esophageal adenocarcinomas defines genomic biomarkers for the clinic.
Frankell AM, Jammula S, Li X, Contino G, Killcoyne S, Abbas S, Perner J, Bower L, Devonshire G, Ococks E, Grehan N, Mok J, O'Donovan M, MacRae S, Eldridge MD, Tavaré S; Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) Consortium; Fitzgerald RC. Frankell AM, et al. Nat Genet. 2019 Mar;51(3):506-516. doi: 10.1038/s41588-018-0331-5. Epub 2019 Feb 4. Nat Genet. 2019. PMID: 30718927 Free PMC article.
61 results