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Lipid regulation of the glucagon receptor family.
Oqua AI, Manchanda Y, McGlone ER, Jones B, Rouse S, Tomas A. Oqua AI, et al. Among authors: tomas a. J Endocrinol. 2024 May 6;261(3):e230335. doi: 10.1530/JOE-23-0335. Print 2024 Jun 1. J Endocrinol. 2024. PMID: 38614123 Free PMC article. Review.
Hepatocyte cholesterol content modulates glucagon receptor signalling.
McGlone ER, Ansell TB, Dunsterville C, Song W, Carling D, Tomas A, Bloom SR, Sansom MSP, Tan T, Jones B. McGlone ER, et al. Among authors: tomas a. Mol Metab. 2022 Sep;63:101530. doi: 10.1016/j.molmet.2022.101530. Epub 2022 Jun 16. Mol Metab. 2022. PMID: 35718339 Free PMC article.
Agonist-induced membrane nanodomain clustering drives GLP-1 receptor responses in pancreatic beta cells.
Buenaventura T, Bitsi S, Laughlin WE, Burgoyne T, Lyu Z, Oqua AI, Norman H, McGlone ER, Klymchenko AS, Corrêa IR Jr, Walker A, Inoue A, Hanyaloglu A, Grimes J, Koszegi Z, Calebiro D, Rutter GA, Bloom SR, Jones B, Tomas A. Buenaventura T, et al. Among authors: tomas a. PLoS Biol. 2019 Aug 20;17(8):e3000097. doi: 10.1371/journal.pbio.3000097. eCollection 2019 Aug. PLoS Biol. 2019. PMID: 31430273 Free PMC article.
Genetic and biased agonist-mediated reductions in β-arrestin recruitment prolong cAMP signaling at glucagon family receptors.
Jones B, McGlone ER, Fang Z, Pickford P, Corrêa IR Jr, Oishi A, Jockers R, Inoue A, Kumar S, Görlitz F, Dunsby C, French PMW, Rutter GA, Tan T, Tomas A, Bloom SR. Jones B, et al. Among authors: tomas a. J Biol Chem. 2021 Jan-Jun;296:100133. doi: 10.1074/jbc.RA120.016334. Epub 2020 Dec 4. J Biol Chem. 2021. PMID: 33268378 Free PMC article.
In vivo and in vitro characterization of GL0034, a novel long-acting glucagon-like peptide-1 receptor agonist.
Jones B, Burade V, Akalestou E, Manchanda Y, Ramchunder Z, Carrat G, Nguyen-Tu MS, Marchetti P, Piemonti L, Leclerc I, Thennati R, Vilsboll T, Thorens B, Tomas A, Rutter GA. Jones B, et al. Among authors: tomas a. Diabetes Obes Metab. 2022 Nov;24(11):2090-2101. doi: 10.1111/dom.14794. Epub 2022 Jul 18. Diabetes Obes Metab. 2022. PMID: 35676825 Free PMC article.
452 results