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Tools for a personalized tacrolimus dose adjustment in the follow-up of renal transplant recipients. Metabolizing phenotype according to CYP3A genetic polymorphisms versus concentration-dose ratio.
Vidal-Alabró A, Colom H, Fontova P, Cerezo G, Melilli E, Montero N, Coloma A, Manonelles A, Favà A, Cruzado JM, Torras J, Grinyó JM, Lloberas N. Vidal-Alabró A, et al. Among authors: grinyo jm. Nefrologia (Engl Ed). 2024 Mar-Apr;44(2):204-216. doi: 10.1016/j.nefroe.2024.03.019. Epub 2024 Apr 12. Nefrologia (Engl Ed). 2024. PMID: 38614890 Free article.
Measurement of calcineurin activity in peripheral blood mononuclear cells by ultra-high performance liquid chromatography-tandem mass spectrometry. Renal transplant recipients application (pharmacodynamic monitoring).
Fontova P, Rigo-Bonnin R, Vidal-Alabró A, Cerezo G, Bestard O, Cruzado JM, Torras J, Grinyó JM, Lloberas N. Fontova P, et al. Among authors: grinyo jm. Clin Chim Acta. 2019 Aug;495:287-293. doi: 10.1016/j.cca.2019.04.079. Epub 2019 Apr 27. Clin Chim Acta. 2019. PMID: 31039337
Validation and evaluation of four sample preparation methods for the quantification of intracellular tacrolimus in peripheral blood mononuclear cells by UHPLC-MS/MS.
van Merendonk LN, Fontova P, Rigo-Bonnin R, Colom H, Vidal-Alabró A, Bestard O, Torras J, Cruzado JM, Grinyó JM, Lloberas N. van Merendonk LN, et al. Among authors: grinyo jm. Clin Chim Acta. 2020 Apr;503:210-217. doi: 10.1016/j.cca.2019.11.033. Epub 2019 Nov 30. Clin Chim Acta. 2020. PMID: 31794770 Free article.
Sustained Inhibition of Calcineurin Activity With a Melt-Dose Once-daily Tacrolimus Formulation in Renal Transplant Recipients.
Fontova P, Colom H, Rigo-Bonnin R, Bestard O, Vidal-Alabró A, van Merendonk LN, Cerezo G, Polo C, Montero N, Melilli E, Manonelles A, Meneghini M, Coloma A, Cruzado JM, Torras J, Grinyó JM, Lloberas N. Fontova P, et al. Among authors: grinyo jm. Clin Pharmacol Ther. 2021 Jul;110(1):238-247. doi: 10.1002/cpt.2220. Epub 2021 Mar 25. Clin Pharmacol Ther. 2021. PMID: 33626199 Free article. Clinical Trial.
Influence of the Circadian Timing System on Tacrolimus Pharmacokinetics and Pharmacodynamics After Kidney Transplantation.
Fontova P, Colom H, Rigo-Bonnin R, van Merendonk LN, Vidal-Alabró A, Montero N, Melilli E, Meneghini M, Manonelles A, Cruzado JM, Torras J, Grinyó JM, Bestard O, Lloberas N. Fontova P, et al. Among authors: grinyo jm. Front Pharmacol. 2021 Mar 17;12:636048. doi: 10.3389/fphar.2021.636048. eCollection 2021. Front Pharmacol. 2021. PMID: 33815118 Free PMC article.
Tacrolimus CYP3A Single-Nucleotide Polymorphisms and Preformed T- and B-Cell Alloimmune Memory Improve Current Pretransplant Rejection-Risk Stratification in Kidney Transplantation.
Crespo E, Vidal-Alabró A, Jouve T, Fontova P, Stein M, Mocka S, Meneghini M, Sefrin A, Hruba P, Gomà M, Torija A, Donadeu L, Favà A, Cruzado JM, Melilli E, Moreso F, Viklicky O, Bemelman F, Reinke P, Grinyó J, Lloberas N, Bestard O. Crespo E, et al. Among authors: grinyo j. Front Immunol. 2022 Jun 27;13:869554. doi: 10.3389/fimmu.2022.869554. eCollection 2022. Front Immunol. 2022. PMID: 35833145 Free PMC article.
The Effect of Intracellular Tacrolimus Exposure on Calcineurin Inhibition in Immediate- and Extended-Release Tacrolimus Formulations.
Fontova P, van Merendonk LN, Vidal-Alabró A, Rigo-Bonnin R, Cerezo G, van Oevelen S, Bestard O, Melilli E, Montero N, Coloma A, Manonelles A, Torras J, Cruzado JM, Grinyó JM, Colom H, Lloberas N. Fontova P, et al. Among authors: grinyo jm. Pharmaceutics. 2023 May 12;15(5):1481. doi: 10.3390/pharmaceutics15051481. Pharmaceutics. 2023. PMID: 37242723 Free PMC article.
324 results