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Transposable elements regulate thymus development and function.
Larouche JD, Laumont CM, Trofimov A, Vincent K, Hesnard L, Brochu S, Côté C, Humeau JF, Bonneil É, Lanoix J, Durette C, Gendron P, Laverdure JP, Richie ER, Lemieux S, Thibault P, Perreault C. Larouche JD, et al. Among authors: durette c. Elife. 2024 Apr 18;12:RP91037. doi: 10.7554/eLife.91037. Elife. 2024. PMID: 38635416 Free PMC article.
Noncoding regions are the main source of targetable tumor-specific antigens.
Laumont CM, Vincent K, Hesnard L, Audemard É, Bonneil É, Laverdure JP, Gendron P, Courcelles M, Hardy MP, Côté C, Durette C, St-Pierre C, Benhammadi M, Lanoix J, Vobecky S, Haddad E, Lemieux S, Thibault P, Perreault C. Laumont CM, et al. Among authors: durette c. Sci Transl Med. 2018 Dec 5;10(470):eaau5516. doi: 10.1126/scitranslmed.aau5516. Sci Transl Med. 2018. PMID: 30518613
Proteogenomics Uncovers a Vast Repertoire of Shared Tumor-Specific Antigens in Ovarian Cancer.
Zhao Q, Laverdure JP, Lanoix J, Durette C, Côté C, Bonneil É, Laumont CM, Gendron P, Vincent K, Courcelles M, Lemieux S, Millar DG, Ohashi PS, Thibault P, Perreault C. Zhao Q, et al. Among authors: durette c. Cancer Immunol Res. 2020 Apr;8(4):544-555. doi: 10.1158/2326-6066.CIR-19-0541. Epub 2020 Feb 11. Cancer Immunol Res. 2020. PMID: 32047025
MAPDP: A Cloud-Based Computational Platform for Immunopeptidomics Analyses.
Courcelles M, Durette C, Daouda T, Laverdure JP, Vincent K, Lemieux S, Perreault C, Thibault P. Courcelles M, et al. Among authors: durette c. J Proteome Res. 2020 Apr 3;19(4):1873-1881. doi: 10.1021/acs.jproteome.9b00859. Epub 2020 Mar 13. J Proteome Res. 2020. PMID: 32108478
Most non-canonical proteins uniquely populate the proteome or immunopeptidome.
Ruiz Cuevas MV, Hardy MP, Hollý J, Bonneil É, Durette C, Courcelles M, Lanoix J, Côté C, Staudt LM, Lemieux S, Thibault P, Perreault C, Yewdell JW. Ruiz Cuevas MV, et al. Among authors: durette c. Cell Rep. 2021 Mar 9;34(10):108815. doi: 10.1016/j.celrep.2021.108815. Cell Rep. 2021. PMID: 33691108 Free PMC article.
Atypical acute myeloid leukemia-specific transcripts generate shared and immunogenic MHC class-I-associated epitopes.
Ehx G, Larouche JD, Durette C, Laverdure JP, Hesnard L, Vincent K, Hardy MP, Thériault C, Rulleau C, Lanoix J, Bonneil E, Feghaly A, Apavaloaei A, Noronha N, Laumont CM, Delisle JS, Vago L, Hébert J, Sauvageau G, Lemieux S, Thibault P, Perreault C. Ehx G, et al. Among authors: durette c. Immunity. 2021 Apr 13;54(4):737-752.e10. doi: 10.1016/j.immuni.2021.03.001. Epub 2021 Mar 18. Immunity. 2021. PMID: 33740418 Free article.
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