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Targeting NRAS via miR-1304-5p or farnesyltransferase inhibition confers sensitivity to ALK inhibitors in ALK-mutant neuroblastoma.
Pucci P, Lee LC, Han M, Matthews JD, Jahangiri L, Schlederer M, Manners E, Sorby-Adams A, Kaggie J, Trigg RM, Steel C, Hare L, James ER, Prokoph N, Ducray SP, Merkel O, Rifatbegovic F, Luo J, Taschner-Mandl S, Kenner L, Burke GAA, Turner SD. Pucci P, et al. Among authors: han m. Nat Commun. 2024 Apr 23;15(1):3422. doi: 10.1038/s41467-024-47771-x. Nat Commun. 2024. PMID: 38653965 Free PMC article.
The targetable kinase PIM1 drives ALK inhibitor resistance in high-risk neuroblastoma independent of MYCN status.
Trigg RM, Lee LC, Prokoph N, Jahangiri L, Reynolds CP, Amos Burke GA, Probst NA, Han M, Matthews JD, Lim HK, Manners E, Martinez S, Pastor J, Blanco-Aparicio C, Merkel O, de Los Fayos Alonso IG, Kodajova P, Tangermann S, Högler S, Luo J, Kenner L, Turner SD. Trigg RM, et al. Among authors: han m. Nat Commun. 2019 Nov 28;10(1):5428. doi: 10.1038/s41467-019-13315-x. Nat Commun. 2019. PMID: 31780656 Free PMC article.
Mitochondrial ferritin upregulation by deferiprone reduced neuronal ferroptosis and improved neurological deficits via NDRG1/Yap pathway in a neonatal rat model of germinal matrix hemorrhage.
Yuan Y, Yang X, Zhao Y, Flores JJ, Huang L, Gu L, Li R, Zhang X, Zhu S, Dong S, Kanamaru H, He Q, Tao Y, Yi K, Han M, Chen X, Wu L, Zhang JH, Xie Z, Tang J. Yuan Y, et al. Among authors: han m. J Cereb Blood Flow Metab. 2024 Sep 24:271678X241252110. doi: 10.1177/0271678X241252110. Online ahead of print. J Cereb Blood Flow Metab. 2024. PMID: 39318194
Deep Learning Estimation of Small Airways Disease from Inspiratory Chest CT is Associated with FEV 1 Decline in COPD.
Chaudhary MFA, Awan HA, Gerard SE, Bodduluri S, Comellas AP, Barjaktarevic IZ, Barr RG, Cooper CB, Galban CJ, Han MK, Curtis JL, Hansel NN, Krishnan JA, Menchaca MG, Martinez FJ, Ohar J, Vargas Buonfiglio LG, Paine R, Bhatt SP, Hoffman EA, Reinhardt JM. Chaudhary MFA, et al. Among authors: han mk. medRxiv [Preprint]. 2024 Sep 11:2024.09.10.24313079. doi: 10.1101/2024.09.10.24313079. medRxiv. 2024. PMID: 39314974 Free PMC article. Preprint.
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