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"Dual Anta-Inhibitors" of the A2A Adenosine Receptor and Casein Kinase CK1delta: Synthesis, Biological Evaluation, and Molecular Modeling Studies.
Spinaci A, Buccioni M, Catarzi D, Cui C, Colotta V, Dal Ben D, Cescon E, Francucci B, Grieco I, Lambertucci C, Marucci G, Bassani D, Pavan M, Varano F, Federico S, Spalluto G, Moro S, Volpini R. Spinaci A, et al. Among authors: colotta v. Pharmaceuticals (Basel). 2023 Jan 23;16(2):167. doi: 10.3390/ph16020167. Pharmaceuticals (Basel). 2023. PMID: 37259317 Free PMC article.
Design and Synthesis of Novel Thiazolo[5,4-d]pyrimidine Derivatives with High Affinity for Both the Adenosine A1 and A2A Receptors, and Efficacy in Animal Models of Depression.
Varano F, Catarzi D, Vigiani E, Dal Ben D, Buccioni M, Marucci G, Di Cesare Mannelli L, Lucarini E, Ghelardini C, Volpini R, Colotta V. Varano F, et al. Among authors: colotta v. Pharmaceuticals (Basel). 2021 Jul 9;14(7):657. doi: 10.3390/ph14070657. Pharmaceuticals (Basel). 2021. PMID: 34358083 Free PMC article.
4-Heteroaryl Substituted Amino-3,5-Dicyanopyridines as New Adenosine Receptor Ligands: Novel Insights on Structure-Activity Relationships and Perspectives.
Catarzi D, Varano F, Vigiani E, Calenda S, Melani F, Varani K, Vincenzi F, Pasquini S, Mennini N, Nerli G, Dal Ben D, Volpini R, Colotta V. Catarzi D, et al. Among authors: colotta v. Pharmaceuticals (Basel). 2022 Apr 14;15(4):478. doi: 10.3390/ph15040478. Pharmaceuticals (Basel). 2022. PMID: 35455475 Free PMC article.
7-Amino-2-phenylpyrazolo[4,3-d]pyrimidine derivatives: structural investigations at the 5-position to target human A₁ and A(2A) adenosine receptors. Molecular modeling and pharmacological studies.
Squarcialupi L, Colotta V, Catarzi D, Varano F, Betti M, Varani K, Vincenzi F, Borea PA, Porta N, Ciancetta A, Moro S. Squarcialupi L, et al. Among authors: colotta v. Eur J Med Chem. 2014 Sep 12;84:614-27. doi: 10.1016/j.ejmech.2014.07.060. Epub 2014 Jul 19. Eur J Med Chem. 2014. PMID: 25063944
Discovery of first-in-class multi-target adenosine A2A receptor antagonists-carbonic anhydrase IX and XII inhibitors. 8-Amino-6-aryl-2-phenyl-1,2,4-triazolo [4,3-a]pyrazin-3-one derivatives as new potential antitumor agents.
Ceni C, Catarzi D, Varano F, Ben DD, Marucci G, Buccioni M, Volpini R, Angeli A, Nocentini A, Gratteri P, Supuran CT, Colotta V. Ceni C, et al. Among authors: colotta v. Eur J Med Chem. 2020 Sep 1;201:112478. doi: 10.1016/j.ejmech.2020.112478. Epub 2020 Jun 12. Eur J Med Chem. 2020. PMID: 32659606
104 results