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mTOR inhibition alleviates mitochondrial disease in a mouse model of Leigh syndrome.
Johnson SC, Yanos ME, Kayser EB, Quintana A, Sangesland M, Castanza A, Uhde L, Hui J, Wall VZ, Gagnidze A, Oh K, Wasko BM, Ramos FJ, Palmiter RD, Rabinovitch PS, Morgan PG, Sedensky MM, Kaeberlein M. Johnson SC, et al. Among authors: kayser eb. Science. 2013 Dec 20;342(6165):1524-8. doi: 10.1126/science.1244360. Epub 2013 Nov 14. Science. 2013. PMID: 24231806 Free PMC article.
Regional metabolic signatures in the Ndufs4(KO) mouse brain implicate defective glutamate/α-ketoglutarate metabolism in mitochondrial disease.
Johnson SC, Kayser EB, Bornstein R, Stokes J, Bitto A, Park KY, Pan A, Sun G, Raftery D, Kaeberlein M, Sedensky MM, Morgan PG. Johnson SC, et al. Among authors: kayser eb. Mol Genet Metab. 2020 Jun;130(2):118-132. doi: 10.1016/j.ymgme.2020.03.007. Epub 2020 Apr 3. Mol Genet Metab. 2020. PMID: 32331968 Free PMC article.
Isoflurane inhibition of endocytosis is an anesthetic mechanism of action.
Jung S, Zimin PI, Woods CB, Kayser EB, Haddad D, Reczek CR, Nakamura K, Ramirez JM, Sedensky MM, Morgan PG. Jung S, et al. Among authors: kayser eb. Curr Biol. 2022 Jul 25;32(14):3016-3032.e3. doi: 10.1016/j.cub.2022.05.037. Epub 2022 Jun 9. Curr Biol. 2022. PMID: 35688155 Free PMC article.
Ketamine and Mitochondrial Function.
Morgan PG, Sedensky MM, Kayser EB. Morgan PG, et al. Among authors: kayser eb. Anesth Analg. 2016 Mar;122(3):917-918. doi: 10.1213/ANE.0000000000000872. Anesth Analg. 2016. PMID: 26891403 No abstract available.
24 results