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A randomized, phase 1, placebo-controlled trial of APG-157 in oral cancer demonstrates systemic absorption and an inhibitory effect on cytokines and tumor-associated microbes.
Basak SK, Bera A, Yoon AJ, Morselli M, Jeong C, Tosevska A, Dong TS, Eklund M, Russ E, Nasser H, Lagishetty V, Guo R, Sajed D, Mudgal S, Mehta P, Avila L, Srivastava M, Faull K, Jacobs J, Pellegrini M, Shin DS, Srivatsan ES, Wang MB. Basak SK, et al. Cancer. 2020 Apr 15;126(8):1668-1682. doi: 10.1002/cncr.32644. Epub 2020 Feb 5. Cancer. 2020. PMID: 32022261 Free article. Clinical Trial.
Gigaxonin Suppresses Epithelial-to-Mesenchymal Transition of Human Cancer Through Downregulation of Snail.
Veena MS, Gahng JJ, Alani M, Ko AY, Basak SK, Liu IY, Hwang KJ, Chatoff JR, Venkatesan N, Morselli M, Yan W, Ali I, Kaczor-Urbanowicz KE, Gowda BS, Frost P, Pellegrini M, Moatamed NA, Wilczynski SP, Bomont P, Wang MB, Shin DS, Srivatsan ES. Veena MS, et al. Among authors: basak sk. Cancer Res Commun. 2024 Mar 8;4(3):706-722. doi: 10.1158/2767-9764.CRC-23-0331. Cancer Res Commun. 2024. PMID: 38421310 Free PMC article.
Cystatin E/M Suppresses Tumor Cell Growth through Cytoplasmic Retention of NF-κB.
Soh H, Venkatesan N, Veena MS, Ravichandran S, Zinabadi A, Basak SK, Parvatiyar K, Srivastava M, Liang LJ, Gjertson DW, Torres JZ, Moatamed NA, Srivatsan ES. Soh H, et al. Among authors: basak sk. Mol Cell Biol. 2016 May 31;36(12):1776-92. doi: 10.1128/MCB.00878-15. Print 2016 Jun 15. Mol Cell Biol. 2016. PMID: 27090639 Free PMC article.
p16 Protein and gigaxonin are associated with the ubiquitination of NFκB in cisplatin-induced senescence of cancer cells.
Veena MS, Wilken R, Zheng JY, Gholkar A, Venkatesan N, Vira D, Ahmed S, Basak SK, Dalgard CL, Ravichandran S, Batra RK, Kasahara N, Elashoff D, Fishbein MC, Whitelegge JP, Torres JZ, Wang MB, Srivatsan ES. Veena MS, et al. Among authors: basak sk. J Biol Chem. 2014 Dec 12;289(50):34921-37. doi: 10.1074/jbc.M114.568543. Epub 2014 Oct 20. J Biol Chem. 2014. PMID: 25331947 Free PMC article.
Dysregulation of hsa-miR-34a and hsa-miR-449a leads to overexpression of PACS-1 and loss of DNA damage response (DDR) in cervical cancer.
Veena MS, Raychaudhuri S, Basak SK, Venkatesan N, Kumar P, Biswas R, Chakrabarti R, Lu J, Su T, Gallagher-Jones M, Morselli M, Fu H, Pellegrini M, Goldstein T, Aladjem MI, Rettig MB, Wilczynski SP, Shin DS, Srivatsan ES. Veena MS, et al. Among authors: basak sk. J Biol Chem. 2020 Dec 11;295(50):17169-17186. doi: 10.1074/jbc.RA120.014048. Epub 2020 Oct 7. J Biol Chem. 2020. PMID: 33028635 Free PMC article.
826 results