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Nucleobase adducts bind MR1 and stimulate MR1-restricted T cells.
Vacchini A, Chancellor A, Yang Q, Colombo R, Spagnuolo J, Berloffa G, Joss D, Øyås O, Lecchi C, De Simone G, Beshirova A, Nosi V, Loureiro JP, Morabito A, De Gregorio C, Pfeffer M, Schaefer V, Prota G, Zippelius A, Stelling J, Häussinger D, Brunelli L, Villalta P, Lepore M, Davoli E, Balbo S, Mori L, De Libero G. Vacchini A, et al. Among authors: haussinger d. Sci Immunol. 2024 May 10;9(95):eadn0126. doi: 10.1126/sciimmunol.adn0126. Epub 2024 May 10. Sci Immunol. 2024. PMID: 38728413
A novel self-lipid antigen targets human T cells against CD1c(+) leukemias.
Lepore M, de Lalla C, Gundimeda SR, Gsellinger H, Consonni M, Garavaglia C, Sansano S, Piccolo F, Scelfo A, Häussinger D, Montagna D, Locatelli F, Bonini C, Bondanza A, Forcina A, Li Z, Ni G, Ciceri F, Jenö P, Xia C, Mori L, Dellabona P, Casorati G, De Libero G. Lepore M, et al. Among authors: haussinger d. J Exp Med. 2014 Jun 30;211(7):1363-77. doi: 10.1084/jem.20140410. Epub 2014 Jun 16. J Exp Med. 2014. PMID: 24935257 Free PMC article. Clinical Trial.
Human T cells engineered with a leukemia lipid-specific TCR enables donor-unrestricted recognition of CD1c-expressing leukemia.
Consonni M, Garavaglia C, Grilli A, de Lalla C, Mancino A, Mori L, De Libero G, Montagna D, Casucci M, Serafini M, Bonini C, Häussinger D, Ciceri F, Bernardi M, Mastaglio S, Bicciato S, Dellabona P, Casorati G. Consonni M, et al. Among authors: haussinger d. Nat Commun. 2021 Aug 11;12(1):4844. doi: 10.1038/s41467-021-25223-0. Nat Commun. 2021. PMID: 34381053 Free PMC article.
Pseudocontact Shifts in Biomolecular NMR Spectroscopy.
Müntener T, Joss D, Häussinger D, Hiller S. Müntener T, et al. Among authors: haussinger d. Chem Rev. 2022 May 25;122(10):9422-9467. doi: 10.1021/acs.chemrev.1c00796. Epub 2022 Jan 10. Chem Rev. 2022. PMID: 35005884 Review.
1,107 results