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MAdCAM-1 co-stimulation combined with retinoic acid and TGF-β induces blood CD8+ T cells to adopt a gut CD101+ TRM phenotype.
Girard A, Vimonpatranon S, Chan A, Jiang A, Huang DW, Virtaneva K, Kanakabandi K, Martens C, Goes LR, Soares MA, Licavoli I, McMurry J, Doan P, Wertz S, Wei D, Ryk DV, Ganesan S, Hwang IY, Kehrl JH, Martinelli E, Arthos J, Cicala C. Girard A, et al. Among authors: goes lr. Mucosal Immunol. 2024 Aug;17(4):700-712. doi: 10.1016/j.mucimm.2024.04.004. Epub 2024 May 8. Mucosal Immunol. 2024. PMID: 38729611 Free article.
MAdCAM costimulation through Integrin-α4β7 promotes HIV replication.
Nawaz F, Goes LR, Ray JC, Olowojesiku R, Sajani A, Ansari AA, Perrone I, Hiatt J, Van Ryk D, Wei D, Waliszewski M, Soares MA, Jelicic K, Connors M, Migueles SA, Martinelli E, Villinger F, Cicala C, Fauci AS, Arthos J. Nawaz F, et al. Among authors: goes lr. Mucosal Immunol. 2018 Sep;11(5):1342-1351. doi: 10.1038/s41385-018-0044-1. Epub 2018 Jun 6. Mucosal Immunol. 2018. PMID: 29875402 Free PMC article.
MAdCAM-1 costimulation in the presence of retinoic acid and TGF-β promotes HIV infection and differentiation of CD4+ T cells into CCR5+ TRM-like cells.
Vimonpatranon S, Goes LR, Chan A, Licavoli I, McMurry J, Wertz SR, Arakelyan A, Huang D, Jiang A, Huang C, Zhou J, Yolitz J, Girard A, Van Ryk D, Wei D, Hwang IY, Martens C, Kanakabandi K, Virtaneva K, Ricklefs S, Darwitz BP, Soares MA, Pattanapanyasat K, Fauci AS, Arthos J, Cicala C. Vimonpatranon S, et al. Among authors: goes lr. PLoS Pathog. 2023 Mar 10;19(3):e1011209. doi: 10.1371/journal.ppat.1011209. eCollection 2023 Mar. PLoS Pathog. 2023. PMID: 36897929 Free PMC article.
The V2 domain of HIV gp120 mimics an interaction between CD4 and integrin ⍺4β7.
Van Ryk D, Vimonpatranon S, Hiatt J, Ganesan S, Chen N, McMurry J, Garba S, Min S, Goes LR, Girard A, Yolitz J, Licavoli I, Wei D, Huang D, Soares MA, Martinelli E, Cicala C, Arthos J. Van Ryk D, et al. Among authors: goes lr. PLoS Pathog. 2023 Dec 8;19(12):e1011860. doi: 10.1371/journal.ppat.1011860. eCollection 2023 Dec. PLoS Pathog. 2023. PMID: 38064524 Free PMC article.
SARS-CoV-2 genomic and quasispecies analyses in cancer patients reveal relaxed intrahost virus evolution.
Siqueira JD, Goes LR, Alves BM, de Carvalho PS, Cicala C, Arthos J, Viola JPB, de Melo AC, Soares MA. Siqueira JD, et al. Among authors: goes lr. bioRxiv [Preprint]. 2020 Aug 26:2020.08.26.267831. doi: 10.1101/2020.08.26.267831. bioRxiv. 2020. Update in: Virus Evol. 2021 Feb 16;7(1):veab013. doi: 10.1093/ve/veab013. PMID: 32869023 Free PMC article. Updated. Preprint.
The V2 loop of HIV gp120 delivers costimulatory signals to CD4+ T cells through Integrin α4β7 and promotes cellular activation and infection.
Goes LR, Sajani A, Sivro A, Olowojesiku R, Ray JC, Perrone I, Yolitz J, Girard A, Leyre L, Wibmer CK, Morris L, Gorini G, Franchini G, Mason RD, Roederer M, Mehandru S, Soares MA, Cicala C, Fauci AS, Arthos J. Goes LR, et al. Proc Natl Acad Sci U S A. 2020 Dec 22;117(51):32566-32573. doi: 10.1073/pnas.2011501117. Epub 2020 Dec 7. Proc Natl Acad Sci U S A. 2020. PMID: 33288704 Free PMC article.
15 results